Journal
IMMUNOLOGY LETTERS
Volume 192, Issue -, Pages 7-11Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.imlet.2017.09.013
Keywords
Mucosal-associated invariant T cell (MAIT); Cytokine; T cell receptor; Effector function; Barrier tissue; Commensal bacteria; Infection
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Funding
- NIDCR NIH HHS [DP2 DE023321] Funding Source: Medline
- NIGMS NIH HHS [T32 GM007270] Funding Source: Medline
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We review the recent human mucosal-associated invariant T (MAIT) cell literature to examine the signals that control MAIT cell activation. We discuss these signals in context of MAIT cell function in mucosal barrier tissues and address how MAIT cells avoid responding to commensal bacteria, while maintaining responsiveness to infections.
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