Related references
Note: Only part of the references are listed.RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
K. Newton et al.
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JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
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JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
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SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
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CELL (2014)
Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration
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CELL DEATH AND DIFFERENTIATION (2014)
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
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CELL RESEARCH (2014)
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CURRENT OPINION IN IMMUNOLOGY (2014)
The Necroptosis Adaptor RIPK3 Promotes Injury-Induced Cytokine Expression and Tissue Repair
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IMMUNITY (2014)
RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity
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MOLECULAR CELL (2014)
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
Marius Dannappel et al.
NATURE (2014)
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
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NATURE CELL BIOLOGY (2014)
Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
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Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
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SCIENCE (2014)
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
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CELL REPORTS (2014)
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Positive and negative phosphorylation regulates RIP1-and RIP3-induced programmed necrosis
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BIOCHEMICAL JOURNAL (2013)
TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species
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CELL (2013)
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Absence of Receptor Interacting Protein Kinase 3 Prevents Ethanol-Induced Liver Injury
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HEPATOLOGY (2013)
Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
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IMMUNITY (2013)
Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling
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JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Proapoptotic Chemotherapeutic Drugs Induce Noncanonical Processing and Release of IL-1β via Caspase-8 in Dendritic Cells
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JOURNAL OF IMMUNOLOGY (2013)
Receptor Interacting Protein Kinase-Mediated Necrosis Contributes to Cone and Rod Photoreceptor Degeneration in the Retina Lacking Interphotoreceptor Retinoid-Binding Protein
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JOURNAL OF NEUROSCIENCE (2013)
Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development
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CELL REPORTS (2013)
Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis
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CELL REPORTS (2013)
RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8-and JNK-Dependent Compensatory Cell Proliferation
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CELL REPORTS (2013)
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
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CELL (2012)
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
Jason W. Upton et al.
CELL HOST & MICROBE (2012)
Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
James E. Vince et al.
IMMUNITY (2012)
Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1β and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner
Lukas Bossaller et al.
JOURNAL OF IMMUNOLOGY (2012)
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
Nirmal Robinson et al.
NATURE IMMUNOLOGY (2012)
Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration
Yusuke Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation
Marion C. Bonnet et al.
IMMUNITY (2011)
RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
Linde Duprez et al.
IMMUNITY (2011)
Structural Determinants of Caspase-9 Inhibition by the Vaccinia Virus Protein, F1L
Eric Yu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
Patrick-Simon Welz et al.
NATURE (2011)
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
William J. Kaiser et al.
NATURE (2011)
Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
Andrew Oberst et al.
NATURE (2011)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
Duan-Wu Zhang et al.
SCIENCE (2009)
Cytomegalovirus m45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1
Jason W. Upton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
Shanshan Feng et al.
CELLULAR SIGNALLING (2007)
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
Mika Aoyagi et al.
PROTEIN SCIENCE (2007)
Kinase RIP3 is dispensable for normal NF-KBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and toll-like receptors 2 and 4
K Newton et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-κB activation
E Meylan et al.
NATURE IMMUNOLOGY (2004)
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
FKM Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis
ST Wasilenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
XQ Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)