Journal
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Volume 37, Issue 1, Pages 153-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2016.08.017
Keywords
Mastocytosis; Mast cell activation syndrome; Anaphylaxis; Risk factors; Triggers; Hymenoptera venom anaphylaxis; Drug-induced anaphylaxis
Categories
Ask authors/readers for more resources
This article updates current knowledge on epidemiology, risk factors, triggers, and management of anaphylaxis in patients with mastocytosis. Hyperactive mast cells and higher number of effector mast cells are speculated to facilitate anaphylaxis in this condition. In children, increased risk is limited to those with extensive skin involvement and high tryptase. In adults, manifestations of anaphylaxis are severe with high frequency of cardiovascular symptoms. Hymenoptera stings are the most common triggers for these reactions; however, idiopathic anaphylaxis and reactions to food or drugs occur. Patients with mastocytosis should be informed about risk of anaphylaxis and prescribing emergency self-medication and installing emergency preparedness before general anesthesia is considered.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available