Journal
NETHERLANDS JOURNAL OF MEDICINE
Volume 78, Issue 5, Pages 282-285Publisher
VAN ZUIDEN COMMUNICATIONS
Keywords
Haemophagocytic lymphohistiocytosis; HSV-2
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Haemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory condition that can be triggered by infections, malignancies, or auto-immune diseases. Here, we present a patient with rapidly progressive HLH triggered by a herpes simplex virus type 2 (HSV-2) primary infection. The patient was successfully treated with intravenous high-dose acyclovir, immunoglobulins, and dexamethasone. This is the first report of HSV-2-associated HLH in an immunocompetent adult patient.
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