Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 81, Pages 12238-12241Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc03883k
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Funding
- Fondazione AIRC per la Ricerca sul Cancro [AIRC IG23566]
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A new dinuclear Pd(i) complex coordinating two bis(NHC) ligands revealed an unsuspected stability despite the unsaturation of the two metal centres. Even more surprisingly, the compound showed high and selective antiproliferative activity against different cancer cell lines and ovarian cancer tumoroids, and the mechanism of action was different from that of cisplatin.
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