Journal
TRAVEL MEDICINE AND INFECTIOUS DISEASE
Volume 38, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tmaid.2020.101884
Keywords
Coronavirus disease 2019; SARS-CoV-2; Clinical characteristics; Demographics; Epidemiology; Clinics
Funding
- Foundation for Science and Technology of Pernambuco(Facepe)-Brazil
- CAPES-Brazil
- International Development Research Centre (IDRC)-Canada [109434]
- Fiocruz Inova Program
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Background: South America is the current epicenter of COVID-19 pandemic. Yet, the epidemiological and clinical features of the disease have not been described in Brazil, the third most affected country in the world. Methods: In this retrospective study, we describe the demographics, epidemiology and clinical features of the first 557 consecutive patients positive for SARS-CoV-2 living in Pernambuco state, Northeast Brazil. Results: The first COVID-19 cases occurred in the high income population. The age of infected patients ranged from 27 days to 97 years with a median of 47 years. The ratio of males to female in the SARS-CoV-2-infected group was 0.83:1. The most common symptom was cough (74.51%), followed by fever (66.79%), dyspnea (56.01%), sore throat (28.19%) and O-2 saturation <95% (24.42%). 86.44% of the lethal cases were patients older than 51 years. The median time from illness onset to diagnosis was 4.0 days (range 0-39 days) Severe patients diagnosed after 14 days of symptoms onset had higher viral load than patients with mild disease. Conclusions: Our study provides important information about COVID-19 in the tropics and will assist physicians and health officials to face the current pandemics as SARS-CoV-2 continues to spread in the human population.
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