Journal
EBIOMEDICINE
Volume 61, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.ebiom.2020.103044
Keywords
Post-sepsis syndrome; Sepsis; Rehospitalization; Quality of life
Funding
- Dutch Kidney Foundation [16OKG06]
- Canadian Institutes for Health Research [FDN-154287]
- Canadian Institutes of Health Research Frederick Banting and Charles Best Canada Graduate Scholarship
- Junior Scientific Masterclass (JSM, UMCG)
Ask authors/readers for more resources
Sepsis is a major health problem worldwide. As the number of sepsis cases increases, so does the number of sepsis survivors who suffer from post-sepsis syndrome after hospital discharge. This syndrome involves deficits in multiple systems, including the immune, cognitive, psychiatric, cardiovascular, and renal systems. Combined, these detrimental consequences lead to rehospitalizations, poorer quality of life, and increased mortality. Understanding the pathophysiology of these issues is crucial to develop new therapeutic opportunities to improve survival rate and quality of life of sepsis survivors. Such novel strategies include modulating the immune system and addressing mitochondrial dysfunction. A sepsis follow-up clinic may be useful to identify long-term health issues associated with post-sepsis syndrome and evaluate existing and novel strategies to improve the lives of sepsis survivors. (C) 2020 The Author(s). Published by Elsevier B.V.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available