4.7 Article

Spontaneous membrane-less multi-compartmentalization via aqueous two-phase separation in complex coacervate micro-droplets

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 84, Pages 12717-12720

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05399f

Keywords

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Funding

  1. EPSRC (Bristol Centre for Functional Nanomaterials) [EP/G036780/1]
  2. ERC Advanced Grant Scheme (EC-2016-ADG) [740235]
  3. BrisSynBio [BB/L01386X/1]
  4. MaxSynBio Consortium - (Federal Ministry of Education and Research (Germany))
  5. MaxSynBio Consortium - (Max Planck Society)
  6. European Research Council (ERC) [740235] Funding Source: European Research Council (ERC)
  7. BBSRC [BB/L01386X/1] Funding Source: UKRI

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Polyelectrolyte/nucleotide multiphase complex coacervate droplets are produced by internalized aqueous two-phase separation and used for the spatially dependent chemical transfer of sugar molecules, providing a step towards the development of membrane-free organelles within coacervate-based protocells.

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