Journal
MEDICAL CLINICS OF NORTH AMERICA
Volume 104, Issue 6, Pages 1051-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.mcna.2020.08.007
Keywords
Prostate cancer; Screening; Prostate-specific antigen; Biomarkers; Magnetic resonance imaging
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Funding
- National Institutes of Health/National Cancer Institute [P30 CA008748, P50 CA92629, U01 CA199338-02]
- Prevent Cancer Foundation
- Sidney Kimmel Center for Prostate and Urologic Cancers
- National Institutes of Health/National Cancer Institute Transition Career Development Award [K22 CA234400]
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This article gives an overview of the current state of the evidence for prostate cancer early detection with prostate-specific antigen (PSA) and summarizes current recommendations from guideline groups. The article reviews the global public health burden and risk factors for prostate cancer with clinical implications as screening tools. Screening studies, novel biomarkers, and MRI are discussed. The article outlines 7 key practice points for primary care physicians and provides a simple schema for facilitating shared decision-making conversations.
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