4.8 Article

Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?

Journal

AUTOPHAGY
Volume 16, Issue 12, Pages 2123-2127

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/15548627.2020.1844940

Keywords

ACE2; chloroquine; dexamethasone; hydroxychloroquine; LC3; macroautophagy; remdesivir; TMPRSS2

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Funding

  1. National Institute of General Medical Sciences [GM131919]

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In the preceding months, the novel SARS-CoV-2 pandemic has devastated global communities. The need for safe and effective prophylactic and therapeutic treatments to combat COVID-19 - the human disease resulting from SARS-CoV-2 infection - is clear. Here, we present recent developments in the effort to combat COVID-19 and consider whether SARS-CoV-2 may potentially interact with the host autophagy pathway.

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