Journal
OPTO-ELECTRONIC ADVANCES
Volume 3, Issue 10, Pages -Publisher
CHINESE ACAD SCI, INST OPTICS & ELECTRONICS, ED OFF OPTO-ELECTRONIC ADV
DOI: 10.29026/oea.2020.200003
Keywords
nonliner optics; microscopic imaging; bio-imaging; label-free; chemical specific
Categories
Funding
- National Natural Science Foundation of China [61722508/61525503/61620106016/61835009/61935012/61961136005]
- Key Project of Department of Education of Guangdong Province [2016KCXTD007]
- Shenzhen Basic Research Project [JCYJ20180305124902165]
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Nonlinear optics, which is a subject for studying the interaction between intense light and materials, has great impact on various research fields. Since many structures in biological tissues exhibit strong nonlinear optical effects, nonlinear optics has been widely applied in biomedical studies. Especially in the aspect of bio-imaging, nonlinear optical techniques can provide rapid, label-free and chemically specific imaging of biological samples, which enable the investigation of biological processes and analysis of samples beyond other microscopy techniques. In this review, we focus on the introduction of nonlinear optical processes and their applications in bio-imaging as well as the recent advances in this filed. Our perspective of this field is also presented.
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