Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 83, Pages 12538-12541Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05895e
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Funding
- NSERC
- NSERC (Canada Research Chair program)
- Canada Foundation for Innovation [35261, 19119]
- Ontario Research Fund
- Kennarshore Inc.
- University of Toronto
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Herein, we describe a protocol for the ring-opening arylation of 1-arylcyclopropyl tosylates, in which boronic acids promote ring-opening and a Ni catalyst facilitates arylation in high regioselectivity. A number of 2-arylated allyl derivatives are synthesized, which are relevant motifs found in biologically active molecules.
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