Journal
HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION
Volume 27, Issue 6, Pages 547-560Publisher
ADIS INT LTD
DOI: 10.1007/s40292-020-00415-9
Keywords
Primary aldosteronism; Renovascular hypertension; Pheochromocytoma; paraganglioma; Cushing’ s syndrome; Obstructive sleep apnea
Categories
Funding
- Universita degli Studi di Padova within the CRUI-CARE Agreement
- European Cooperation in Science and Technology [ADMIRE BM1301, ENSAT-HT 633983]
- Societa Italiana dell'Ipertensione Arteriosa
- FORICA (Foundation for advanced Research In Hypertension and Cardiovascular diseases)
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The vast majority of hypertensive patients are never sought for a cause of their high blood pressure, i.e. for a 'secondary' form of arterial hypertension. This under detection explains why only a tiny percentage of hypertensive patients are ultimately diagnosed with a secondary form of arterial hypertension. The prevalence of these forms is, therefore, markedly underestimated, although, they can involve as many as one-third of the cases among referred patients and up to half of those with difficult to treat hypertension. The early detection of a secondary form is crucial, because if diagnosed in a timely manner, these forms can be cured at long-term, and even when cure cannot be achieved, their diagnosis provides a better control of high blood pressure, and allows prevention of hypertension-mediated organ damage, and related cardiovascular complications. Enormous progress has been made in the understanding, diagnostic work-up, and management of secondary hypertension in the last decades. The aim of this minireview is, therefore, to provide updated concise information on the screening, diagnosis, and management of the most common forms, including primary aldosteronism, renovascular hypertension, pheochromocytoma and paraganglioma, Cushing's syndrome, and obstructive sleep apnea.
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