Journal
CHEMICAL SOCIETY REVIEWS
Volume 49, Issue 22, Pages 8065-8087Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cs00215a
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Funding
- State Key Research Development Program of China [2019YFB2203503]
- National Natural Science Fund [61875138, 61435010, 81871358, U1801254, 61961136001]
- Science and Technology Innovation Commission of Shenzhen [KQTD2015032416270385, JCYJ20180307164612205, GJHZ20180928160209731]
- CRI project of the National Research Foundation of Korea [2018R1A3B1052702]
- Natural Science Foundation of Guangdong Province [2020A151501612]
- Guangdong Basic and Applied Basic Research Foundation [2019B1515120043]
- Science and Technology Project of Shenzhen [JCYJ20180508152903208]
- Longhua District Science and Innovation Commission Project Grants of Shenzhen [JCYJ201904]
- Instrumental Analysis Center of Shenzhen University (Xili Campus)
- National Research Foundation of Korea [4120200213669] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Optical techniques using developed laser and optical devices have made a profound impact on modern medicine, with biomedical optics becoming an emerging field. Sophisticated technologies have been developed in cancer nanomedicine, such as photothermal therapy and photodynamic therapy, among others. However, single-mode phototherapy cannot completely treat persistent tumors, with the challenges of relapse or metastasis remaining; therefore, combinatorial strategies are being developed. In this review, the role of light in cancer therapy and the challenges of phototherapy are discussed. The development of combinatorial strategies with other therapeutic methods, including chemotherapy, immunotherapy, gene therapy, and radiotherapy, is presented and future directions are further discussed. This review aims to highlight the significance of light in cancer therapy and discuss the combinatorial strategies that show promise in addressing the challenges of phototherapy.
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