Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 21, Pages -Publisher
MDPI
DOI: 10.3390/ijms21218390
Keywords
androgenic alopecia; alopecia areata; mesenchymal stem cells; advanced medical therapies; tissue engineering; gene therapy
Funding
- Instituto de Salud Carlos III (European Regional Development Fund A way to make Europe) [PI-17/02083]
- Ministry of Health of the Andalusian Regional Government [SAS PI-0458-2016, AML PIGE-0249-2019]
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Alopecia is a challenging condition for both physicians and patients. Several topical, intralesional, oral, and surgical treatments have been developed in recent decades, but some of those therapies only provide partial improvement. Advanced medical therapies are medical products based on genes, cells, and/or tissue engineering products that have properties in regenerating, repairing, or replacing human tissue. In recent years, numerous applications have been described for advanced medical therapies. With this background, those therapies may have a role in the treatment of various types of alopecia such as alopecia areata and androgenic alopecia. The aim of this review is to provide dermatologists an overview of the different advanced medical therapies that have been applied in the treatment of alopecia, by reviewing clinical and basic research studies as well as ongoing clinical trials.
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