Journal
CRYSTENGCOMM
Volume 17, Issue 34, Pages 6566-6574Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ce01208b
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [81273479, 81402898]
- Shanghai Institute of Materia Medica New-Star Plan B
Ask authors/readers for more resources
Four dapsone-flavone cocrystals were synthesized, including three polymorphic 1 : 1 cocrystals and a 1 : 2 cocrystal. Single crystal structures were disclosed, and the differences in H-bonding interactions were illustrated by comparison of the crystal structures and Hirshfeld surface analysis. The various cocrystals were fully characterized by X-ray powder diffraction, FTIR and thermal analysis. The solubilities, dissolution rates and form transformations in solution were determined. The phase transformation experiments revealed complex phase transformations among the cocrystals. Solid-state transformations among different stoichiometries were also observed in the dapsone-flavone system.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available