4.7 Article

Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

Journal

EMERGING INFECTIOUS DISEASES
Volume 26, Issue 12, Pages 3025-3029

Publisher

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2612.203386

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Funding

  1. Japan Society for the Promotion of Science [17K19319]
  2. Grants-in-Aid for Scientific Research [17K19319] Funding Source: KAKEN

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Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

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