Journal
SCIENCE PROGRESS
Volume 103, Issue 4, Pages -Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0036850420964317
Keywords
Post-translational modification; protein secretion; bacterial pathogens; bacterial virulence factors; proteomics; methylation; acetylation; glycosylation; lipidation
Funding
- BBSRC DTP
- Evelyn Trust (Cambridge)
- Cystic Fibrosis Trust
- British Lung Foundation
- BBSRC
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Protein secretion is almost universally employed by bacteria. Some proteins are retained on the cell surface, whereas others are released into the extracellular milieu, often playing a key role in virulence. In this review, we discuss the diverse types and potential functions of post-translational modifications (PTMs) occurring to extracellular bacterial proteins.
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