Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 88, Pages 13657-13660Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05986b
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Funding
- Natural Science Foundation of Anhui Province [1908085MB54]
- Key Research and Development Projects of Anhui Province [202004a07020018]
- Major project of Anhui Provincial Department of Education [KJ2019ZD58]
- National Natural Science Foundation of China [21890740, 21890742, 21975019, 21727815]
- Basic Research Business Fund of Central Universities [FRF-TP-18-020A1, FRF-BD-2014A]
- China Postdoctoral Science Foundation [2018 M631332]
- Wanjiang scholar Award of Anhui Province
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We report an easy and efficient approach based on a target-induced molecular-switch on triple-helix DNA (THD)-functionalized carbon nanotubes (CNTs) for the simultaneous visual detection of nucleic acids and proteins with a lateral flow nucleic acid biosensor. The assay had the capability to detect a minimum of 25 pM target DNA and 0.25 nM thrombin simultaneously within 20 min.
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