Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 92, Pages 14373-14376Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05196a
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Novel tetraplatinated metalloporphyrin-based photosensitizers (PSs) are reported, which show excellent phototoxic indexes (PIs) up to 5800 against HeLa cells, which is, to the best of our knowledge, the highest value reported for any porphyrin so far. Furthermore, Zn-67 isotope labelling allowed the determination of the ratio of zinc to platinum inside the cells using ICP-MS.
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