Journal
BIOMARKER RESEARCH
Volume 8, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s40364-020-00240-1
Keywords
Tumor heterogeneity; Circulating tumor cells; Drug resistance; Single-cell sequencing
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Funding
- Jiangsu Provincial Key Research and Development Special Fund [BE2015666]
- Jiangsu Innovative team leading talent fund [CXTDC2016006]
- Jiangsu Natural Science Foundation [BK20171304]
- Jiangsu six high peak talent fund [WSW-205]
- Jiangsu 333 talent fund [BRA2016140]
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Malignant tumor is a largely harmful disease worldwide. The cure rate of malignant tumors increases with the continuous discovery of anti-tumor drugs and the optimisation of chemotherapy options. However, drug resistance of tumor cells remains a massive obstacle in the treatment of anti-tumor drugs. The heterogeneity of malignant tumors makes studying it further difficult for us. In recent years, using single-cell sequencing technology to study and analyse circulating tumor cells can avoid the interference of tumor heterogeneity and provide a new perspective for us to understand tumor drug resistance.
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