Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 91, Pages 14183-14186Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05330a
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A hepatocyte-targeting fluorescent N2H4 probe, GHP, was first designed and synthesized employing N-acetylgalactosamine (GalNAc) as the hepatocyte-targeting group and 3-nitrophthalimide as the recognition moiety. The probe can be used to selectively image N2H4 produced by the hydrolysis of isoniazid in HepG2 cells and the liver of zebrafish in situ.
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