Journal
CLINICS IN ORTHOPEDIC SURGERY
Volume 12, Issue 4, Pages 417-429Publisher
KOREAN ORTHOPAEDIC ASSOC
DOI: 10.4055/cios20060
Keywords
Osteogenesis imperfecta; Gene; Bisphosphonate; Intramedullary nailing; Scoliosis
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Funding
- Genome Technology to Business Translation Program of the National Research Foundation (NRF) - Ministry of Science, ICT & Future Planning [NRF-2014M3C9A2064684]
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Osteogenesis imperfecta (OI) is characterized by recurring fractures and limb and spine deformities. With the advent of medical therapeutics and the discovery of causative genes, as well as the introduction of a newly devised intramedullary rod, the general condition and ambulatory function of patients diagnosed with OI have been improved over the past decades. This review covers recent developments in research and management of OI.
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