Journal
TRENDS IN CHEMISTRY
Volume 2, Issue 12, Pages 1126-1140Publisher
CELL PRESS
DOI: 10.1016/j.trechm.2020.10.002
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Funding
- National Key Research and Development Program of China [2018YFE0208500]
- Major Research Plan of the National Natural Science Foundation of China [91963206]
- National Natural Science Foundation of China [52072169, 51627810, 51972164]
- Program for Guangdong Introducing Innovative and Enterpreneurial Teams [2019ZT08L101]
- Natural Science Foundation of Jiangsu Province [SBK2018022120]
- open fund of Wuhan National Laboratory for Optoelectronics [2018WNLOKF020]
- Postgraduate Research & Practice Innovation Program of Jiangsu province [KYCX19_0043]
- Fundamental Research Funds for the Central Universities [14380180]
- Civil Aerospace Technology Research Project: Extraterrestrial in-situ water extraction and photochemical synthesis of hydrogen and oxygen [B0108]
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Photo-therapeutics have attracted increasing attention for the treatment of tumors because of their controllable and tunable nature and low potential for side effects. Photocatalytic materials triggered by targeted wavelengths of light facilitate the generation of reactive oxygen species for tumor DNA damage, allowing for high efficacy at low radiation doses with limited damage of normal tissues. This short review emphasizes the mechanisms and recent breakthroughs achieved in photocatalytic materials for tumor treatment, mainly focusing on light wavelengths in the respective near-infrared (NIR), UV-vis, and X-ray regions. Lastly, current limitations and future perspectives are also highlighted.
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