Journal
CHEMICAL COMMUNICATIONS
Volume 56, Issue 86, Pages 13173-13176Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05126h
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Funding
- AMED [JP19gm0710008]
- MEXT/JSPS KAKENHI [JP16H02606, JP26111012, JP19H05632, JP15H05951, JP19H02826, JP19K22242]
- JSPS Core-to-Core Program [JPJSCCA20170007]
- Graduate Program for Leaders in Life Innovation (GPLLI)
- JSPS stipend
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Spontaneously blinking fluorophores are powerful tools for live-cell super-resolution imaging under physiological conditions. Here we show that quantum-chemical calculations can predict key parameters for fluorophore design. We applied this methodology to develop a spontaneously blinking fluorophore with yellow fluorescence for super-resolution imaging of microtubules in living cells.
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