4.7 Article

In situ detection of hydroxyl radicals in mitochondrial oxidative stress with a nanopipette electrode

Journal

CHEMICAL COMMUNICATIONS
Volume 56, Issue 86, Pages 13225-13228

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cc05889k

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Funding

  1. National Natural Science Foundation of China [21974048, 21635003]
  2. Science and Technology Commission of Shanghai Municipality [19ZR1414600, 18DZ1112700]

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A novel nanopipette electrode was facilely constructed for the detection of OH based on the inner surface wettability. The nanopipettes with excellent analytical performance were empolyed for in situ detection of OH changes induced by mitochondrial oxidative stress and further utilized to study the association of OH with Alzheimer's disease.

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