Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 142, Issue 47, Pages 19862-19867Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.0c09842
Keywords
-
Categories
Funding
- NSF [NSF/DMR-1531283]
- U.S. DOE [DE-AC02-06CH11357]
- Canadian Light Source
- U.S. DOE, Office of Science, Office of Basic Energy Sciences, Catalysis Program [DE-SC0018977]
- Welch Foundation [A-1907]
- Alfred P. Sloan Fellowship
- National Science Foundation (NSF), Division of Chemistry (CHE) [NSF/CHE-1346572]
- National Science Foundation (NSF), Division of Materials Research (DMR) [NSF/CHE-1346572]
- U.S. Department of Energy (DOE) [DE-SC0018977] Funding Source: U.S. Department of Energy (DOE)
Ask authors/readers for more resources
While X-ray crystallography routinely provides structural characterization of kinetically stable pre-catalysts and intermediates, elucidation of the structures of transient reactive intermediates, which are intimately engaged in bond-breaking and -making during catalysis, is generally not possible. Here, we demonstrate in crystallo synthesis of Rh-2 nitrenoids that participate in catalytic C-H amination, and we characterize these transient intermediates as triplet adducts of Rh-2. Further, we observe the impact of coordinating substrate, which is present in excess during catalysis, on the structure of transient Rh-2 nitrenoids. By providing structural characterization of authentic C-H functionalization intermediates, and not kinetically stabilized model complexes, these experiments provide the opportunity to define critical structure-activity relationships.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available