Journal
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
Volume 16, Issue 9, Pages 1325-1358Publisher
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jbn.2020.2976
Keywords
Functional Nanomaterials; Cancer Therapy; Tumor Microenvironment; Drug Delivery; Activable Imaging
Funding
- Hainan Provincial Natural Science Foundation of China [819QN225, 2019RC210]
- National Nature Science Foundation of China [21961010, 21775162, 21864011, 21904030]
- Hainan Provincial Higher Education Research Project [Hnky2019ZD29, Hnky2019ZD-30, Hnky2019ZD-52, Hnky2020-32]
- Talent Program of Hainan Medical University [HYPY201905, XRC180010, XRC180006, XRC180007, XRC190017, XRC190034, XRC190025]
- CAMS Innovation Fund for Medical Sciences [2019-I2M-5-023]
- Nanhai Young-Talent Program of Hainan [20202018, 20202007]
- Hundred-Talent Program [Hainan 2018]
Ask authors/readers for more resources
In recent years, considerable achievements have been made to motivate the construction of tumor microenvironment (TME)-specific functional nanomaterials, which can effectively respond to the inherent pathological and physicochemical conditions in diseased regions to improve the specificity of imaging and drug delivery. Until now, various nano-architectures have been designed to combat cancer effectively and specifically. This review summarizes the latest developments in TME-specific theranostic nanoplatforms based on multifunctional nanomaterials that hold potential for achieving the targeted recognition at tumor sites. Recent progress and achievements have also been summarized for nanosystems that can specifically respond to the TME with various stimulus-responsive strategies and their applications for drug delivery, diagnosis, treatment, and synergistic theranostics of cancer. This review emphasizes the significance of functional nanomaterials in response to tumor stimuli to enhance anticancer treatment efficiency and facilitate development in extensive research fields, including nanoscience, biomedicine, and clinical applications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available