4.3 Article

Safety and Tolerability of Clofazimine in a Cohort of Children With Odontogenic Mycobacterium abscessus Infection

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Publisher

OXFORD UNIV PRESS
DOI: 10.1093/jpids/piz049

Keywords

child; clofazimine; disease outbreaks; nontuberculous mycobacteria; odontogenic infection

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Mycobacterium abscessus infections can be challenging to treat. Clofazimine has excellent in vitro activity against M abscessus, but reports of its use, particularly in children, have been limited. In this study, clofazimine was given to 27 children during an outbreak of odontogenic mycobacterial infections and seemed to be well tolerated as part of a multidrug regimen.

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