Journal
EMERGING INFECTIOUS DISEASES
Volume 26, Issue 12, Pages 2961-2965Publisher
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2612.202308
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- theme-based research scheme of the University Grant Committee [T11-707/15-R]
- Health and Medical Research Fund of the Food and Health Bureau of HKSAR
- Consultancy Service for Enhancing Laboratory Surveillance of Emerging Infectious Disease for the HKSAR Department of Health
- University Development Fund of the University of Hong Kong
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Severe acute respiratory syndrome coronavirus 2 did riot replicate efficiently in 13 bat cell lines whereas severe acute respiratory syndrome coronavirus replicated efficiently in kidney cells of its ancestral host, the Rhinalophus sinicus bat, suggesting different evolutionary origins. Structural modeling showed that RBD/RsACE2 binding may contribute to the differenfial cellular tropism.
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