Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 85, Issue 24, Pages 15780-15800Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.0c01834
Keywords
-
Categories
Funding
- National Institutes of Health [AI130227]
- National Science Foundation [CHE-1954031]
Ask authors/readers for more resources
The importance of post-translational glycosylation in protein structure and function has gained significant clinical relevance recently. The latest developments in glycobiology, glycochemistry, and glycoproteomics have made the field more manageable and relevant to disease progression and immune-response signaling. Here, we summarize the current progress in glycoscience, including the new methodologies that have led to the introduction of programmable and automatic as well as large-scale enzymatic synthesis, and the development of glycan array, glycosylation probes, and inhibitors of carbohydrate-associated enzymes or receptors. These novel methodologies and tools have facilitated our understanding of the significance of glycosylation and development of carbohydrate-derived medicines that bring the field to the next level of scientific and medical significance.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available