Related references
Note: Only part of the references are listed.Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders
Ileena Mitra et al.
PLOS GENETICS (2017)
CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials
Ann Lin et al.
ELIFE (2017)
Congenital Cataract in Mice Is Modified by Proximal Chromosome 15
Bo I. Li et al.
PLOS ONE (2017)
Novel quantitative pigmentation phenotyping enhances genetic association, epistasis, and prediction of human eye colour
Andreas Wollstein et al.
SCIENTIFIC REPORTS (2017)
An empirical fuzzy multifactor dimensionality reduction method for detecting gene-gene interactions
Sangseob Leem et al.
BMC GENOMICS (2017)
Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse Consortium
Danielle A. Fontaine et al.
DIABETES (2016)
Variant haploinsufficiency and phenotypic non-penetrance in PRPF31-associated retinitis pigmentosa
A. M. Rose et al.
CLINICAL GENETICS (2016)
A Case of Mistaken Identity: CD11c-eYFP+ Cells in the Normal Mouse Brain Parenchyma and Neural Retina Display the Phenotype of Microglia, Not Dendritic Cells
Samantha J. Dando et al.
GLIA (2016)
Beware of Your Cre-Ation: lacZ Expression Impairs Neuronal Integrity and Hippocampus-Dependent Memory
J. M. Reichel et al.
HIPPOCAMPUS (2016)
Retinal pigment epithelial integrity is compromised in the developing albino mouse retina
Lena Iwai-Takekoshi et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2016)
Genomic control of neuronal demographics in the retina
Benjamin E. Reese et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2016)
Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain
Vinay S. Mahajan et al.
CELL REPORTS (2016)
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression
David B. West et al.
PLOS GENETICS (2016)
Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium
Shefali Setia Verma et al.
PLOS GENETICS (2016)
Ethnicity-Based Differences in the Association of LOXL1 Polymorphisms with Pseudoexfoliation/Pseudoexfoliative Glaucoma: A Meta-Analysis
Panayiota Founti et al.
ANNALS OF HUMAN GENETICS (2015)
Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease
Jong-Min Lee et al.
CELL (2015)
Gene-gene interaction of CFH, ARMS2, and ARMS2/HTRA1 on the risk of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in Chinese population
L. Huang et al.
EYE (2015)
Vision from next generation sequencing: Multi-dimensional genome-wide analysis for producing gene regulatory networks underlying retinal development, aging and disease
Hyun-Jin Yang et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2015)
Tyro3 Modulates Mertk-Associated Retinal Degeneration
Douglas Vollrath et al.
PLOS GENETICS (2015)
The severity of retinal pathology in homozygous mice is dependent on additional genetic factors
Ulrich F. O. Luhmann et al.
HUMAN MOLECULAR GENETICS (2015)
Genetic Background and Light-Dependent Progression of Photoreceptor Cell Degeneration in Prominin-1 Knockout Mice
Margaret Dellett et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone
Jeroen Declercq et al.
PLOS ONE (2015)
Genetic Evidence for Differential Regulation of Corneal Epithelial and Stromal Thickness
Demelza R. Koehn et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice
Mao Mao et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
Genetic modifier loci of mouse Mfrprd6 identified by quantitative trait locus analysis
Jungyeon Won et al.
EXPERIMENTAL EYE RESEARCH (2014)
Modifier Genes as Therapeutics: The Nuclear Hormone Receptor Rev Erb Alpha (Nr1d1) Rescues Nr2e3 Associated Retinal Disease
Nelly M. Cruz et al.
PLOS ONE (2014)
Spink2 Modulates Apoptotic Susceptibility and Is a Candidate Gene in the Rgcs1 QTL That Affects Retinal Ganglion Cell Death after Optic Nerve Damage
Joel A. Dietz et al.
PLOS ONE (2014)
The Role of Histamine in the Retina: Studies on the Hdc Knockout Mouse
Ursula Greferath et al.
PLOS ONE (2014)
Hemizygous Le-Cre Transgenic Mice Have Severe Eye Abnormalities on Some Genetic Backgrounds in the Absence of LoxP Sites
Natalie J. Dora et al.
PLOS ONE (2014)
Whole Exome Sequencing of a Dominant Retinitis Pigmentosa Family Identifies a Novel Deletion in PRPF31
Adda Villanueva et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)
Strain differences in illumination-dependent structural changes at mouse photoreceptor ribbon synapses
Michaela Fuchs et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2013)
Rd8 Mutation in the Crb1 Gene of CD11c-eYFP Transgenic Reporter Mice Results in Abnormal Numbers of CD11c-Positive Cells in the Retina
Xiangting Chen et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2013)
Genetic modification of corneal neovascularization in Dstn corn1 mice
Sharolyn V. Kawakami-Schulz et al.
MAMMALIAN GENOME (2013)
Null CYP1B1 Genotypes in Primary Congenital and Nondominant Juvenile Glaucoma
Maria-Pilar Lopez-Garrido et al.
OPHTHALMOLOGY (2013)
Germ-Line Recombination Activity of the Widely Used hGFAP-Cre and Nestin-Cre Transgenes
Jiong Zhang et al.
PLOS ONE (2013)
Survey of Common Eye Diseases in Laboratory Mouse Strains
Bo Chang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)
After GWAS: mice to the rescue?
Joerg Ermann et al.
CURRENT OPINION IN IMMUNOLOGY (2012)
Eye-Specific Projections of Retinogeniculate Axons Are Altered in Albino Mice
Alexandra Rebsam et al.
JOURNAL OF NEUROSCIENCE (2012)
Differential Modulation of Retinal Degeneration by Ccl2 and Cx3cr1 Chemokine Signalling
Ulrich F. O. Luhmann et al.
PLOS ONE (2012)
Modifier Genes and the Plasticity of Genetic Networks in Mice
Bruce A. Hamilton et al.
PLOS GENETICS (2012)
CNOT3 Is a Modifier of PRPF31 Mutations in Retinitis Pigmentosa with Incomplete Penetrance
Giulia Venturini et al.
PLOS GENETICS (2012)
An Allele of Microtubule-Associated Protein 1A (Mtap1a) Reduces Photoreceptor Degeneration in Tulp1 and Tub Mutant Mice
Dennis M. Maddox et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
The Rd8 Mutation of the Crb1 Gene Is Present in Vendor Lines of C57BL/6N Mice and Embryonic Stem Cells, and Confounds Ocular Induced Mutant Phenotypes
Mary J. Mattapallil et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
Non-invasive anterior segment and posterior segment optical coherence tomography and phenotypic characterization of aniridia
Kevin Gregory-Evans et al.
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE (2011)
Mispairing C57BL/6 Substrains of Genetically Engineered Mice and Wild-Type Controls Can Lead to Confounding Results as It Did in Studies of JNK2 in Acetaminophen and Concanavalin A Liver Injury
Mohammed Bourdi et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2011)
Nuclear Receptor Rev-erb Alpha (Nr1d1) Functions in Concert with Nr2e3 to Regulate Transcriptional Networks in the Retina
Nissa J. Mollema et al.
PLOS ONE (2011)
Allelic Heterogeneity and Genetic Modifier Loci Contribute to Clinical Variation in Males with X-Linked Retinitis Pigmentosa Due to RPGR Mutations
Abigail T. Fahim et al.
PLOS ONE (2011)
Microarray Analysis of Iris Gene Expression in Mice with Mutations Influencing Pigmentation
Colleen M. Trantow et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Tyrosinase Is the Modifier of Retinoschisis in Mice
Britt A. Johnson et al.
GENETICS (2010)
AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis
Carrie M. Louie et al.
NATURE GENETICS (2010)
Elevated Oxidative Membrane Damage Associated with Genetic Modifiers of Lyst-Mutant Phenotypes
Colleen M. Trantow et al.
PLOS GENETICS (2010)
ABCA4 and ROM1: Implications for Modification of the PRPH2-Associated Macular Dystrophy Phenotype
Charlotte M. Poloschek et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
A Single-Base Substitution within an Intronic Repetitive Element Causes Dominant Retinitis Pigmentosa with Reduced Penetrance
Thomas Rio Frio et al.
HUMAN MUTATION (2009)
NR2E3 Mutations in Enhanced S-Cone Sensitivity Syndrome (ESCS), Goldmann-Favre Syndrome (GFS), Clumped Pigmentary Retinal Degeneration (CPRD), and Retinitis Pigmentosa (RP)
Daniel F. Schorderet et al.
HUMAN MUTATION (2009)
A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies
Hemant Khanna et al.
NATURE GENETICS (2009)
Mouse Forward Genetics in the Study of the Peripheral Nervous System and Human Peripheral Neuropathy
Darlene S. Douglas et al.
NEUROCHEMICAL RESEARCH (2009)
The Severity of Retinal Degeneration in Rp1h Gene-Targeted Mice Is Dependent on Genetic Background
Qin Liu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Discordant phenotypes in fraternal twins having an identical mutation in exon ORF15 of the RPGR gene
Saloni Walia et al.
ARCHIVES OF OPHTHALMOLOGY (2008)
Genetic modification of the schisis phenotype in a mouse model of X-linked retinoschisis
Britt A. Johnson et al.
GENETICS (2008)
Mapping of genetic modifiers of Nr2e3rd7/rd7 that suppress retinal degeneration and restore blue cone cells to normal quantity
Neena B. Haider et al.
MAMMALIAN GENOME (2008)
Iris phenotypes and pigment dispersion caused by genes influencing pigmentation
Michael G. Anderson et al.
PIGMENT CELL & MELANOMA RESEARCH (2008)
The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development
Paul G. Matteson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Genetic modifiers of retinal degeneration in the rd3 mouse
Michael Danciger et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
Analysis of ocular Hypopigmentation in Rab38cht/cht mice
Brian P. Brooks et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Genetic background modifies inner ear and eye phenotypes of Jag1 heterozygous mice
Amy E. Kiernan et al.
GENETICS (2007)
Genotype-phenotype correlation in a German family with a novel complex CRX mutation extending the open reading frame
K. Paunescu et al.
OPHTHALMOLOGY (2007)
Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis
Douglas B. Gould et al.
HUMAN MOLECULAR GENETICS (2007)
Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma
Michael G. Anderson et al.
BMC BIOLOGY (2006)
Variation in retinitis pigmentosa-11 (PRPF31 or RP11) gene expression between symptomatic and asymptomatic patients with dominant RP11 mutations
Carlo Rivolta et al.
HUMAN MUTATION (2006)
Clinical characterisation of a family with retinal dystrophy caused by mutation in the Mertk gene
M. Tschernutter et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2006)
Large-scale mutagenesis and phenotypic screens for the nervous system and behavior in mice
MH Vitaterna et al.
TRENDS IN NEUROSCIENCES (2006)
Mind the gap: analysis of marker-assisted breeding strategies for inbred mouse strains
NJ Armstrong et al.
MAMMALIAN GENOME (2006)
Efficient neuronal gene transfer with AAV8 leads to neurotoxic levels of tau or green fluorescent proteins
RL Klein et al.
MOLECULAR THERAPY (2006)
Uncovering the uncharacterized and unexpected: Unbiased phenotype-driven screens in the mouse
Tamara Caspary et al.
DEVELOPMENTAL DYNAMICS (2006)
Morphological characterization of the retinal degeneration in three strains of mice carrying the rd-3 mutation
KA Linberg et al.
VISUAL NEUROSCIENCE (2005)
Inherited glaucoma in DBA/2J mice: Pertinent disease features for studying the neurodegeneration
RT Libby et al.
VISUAL NEUROSCIENCE (2005)
Genotyping microarray (disease chip) for Leber congenital amaurosis:: Detection of modifier alleles
J Zernant et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Genome-wide strategies for detecting multiple loci that influence complex diseases
J Marchini et al.
NATURE GENETICS (2005)
VSX1 mutational analysis in a series of Italian patients affected by keratoconus: Detection of a novel mutation
L Bisceglia et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
New retinal light damage QTL in mice with the light-sensitive RPE65 LEU variant
M Danciger et al.
MAMMALIAN GENOME (2004)
Mouse genetic corneal disease resulting from transgenic insertional mutagenesis
JS Ramalho et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2004)
To knockout in 129 or in C57BL/6: that is the question
E Seong et al.
TRENDS IN GENETICS (2004)
Quantitative trait locus mapping for age-related cataract severity and synechia prevalence using four-way cross mice
N Wolf et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Expression of PRPF31 mRNA in patients with autosomal dominant retinitis pigmentosa:: A molecular clue for incomplete penetrance?
EN Vithana et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Waddington's widget: Hsp90 and the inheritance of acquired characters
DM Ruden et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2003)
Frizzled 4 gene (FZD4) mutations in patients with familial exudative vitreoretinopathy with variable expressivity
H Kondo et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2003)
Genetic background influences cataractogenesis, but not lens growth deficiency, in Cx50-knockout mice
DA Gerido et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
Genetic modifiers in human development and malformation syndromes, including chaperone proteins
A Slavotinek et al.
HUMAN MOLECULAR GENETICS (2003)
Modification of ocular defects in mouse developmental glaucoma models by tyrosinase
RT Libby et al.
SCIENCE (2003)
Genetic analysis of Nakano Cataract and its modifier genes in mice
M Narita et al.
EXPERIMENTAL EYE RESEARCH (2002)
Novel ENU-induced eye mutations in the mouse: models for human eye disease
C Thaung et al.
HUMAN MOLECULAR GENETICS (2002)
Genetic modification of retinal degeneration in tubby mice
A Ikeda et al.
EXPERIMENTAL EYE RESEARCH (2002)
exma:: an X-linked insertional mutation that disrupts forebrain and eye development
D Cunningham et al.
MAMMALIAN GENOME (2002)
Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice
NB Haider et al.
HUMAN MOLECULAR GENETICS (2001)
Phenotype-genotype relationships in monogenic disease: Lessons from the thalassaemias
DJ Weatherall
NATURE REVIEWS GENETICS (2001)
A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdebrd1) in FVB/N-derived transgenic mice
E Giménez et al.
LABORATORY ANIMALS (2001)
Modifier genes in mice and humans
JH Nadeau
NATURE REVIEWS GENETICS (2001)
A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse
NB Akhmedov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate
NB Haider et al.
NATURE GENETICS (2000)