Journal
HETEROCYCLES
Volume 94, Issue 10, Pages 1819-1846Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/REV-17-867
Keywords
Tetrazole; Biginelli Reaction; Three-Component Reaction; MCR; Aminoazole
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Funding
- Ministry of Higher Education, Malaysia under Fundamental Research Grant Scheme (FRGS)
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5-Aminotetrazole is a useful building block in organic synthesis, including various multicomponent reactions (MCRs). In MCRs, 5-aminotetrazole usually plays a role of 1,3-binucleophilic reagent, but in some reactions, the only reactive centre is an exocyclic amino group of 5-aminotetrazole. This review systematises MCRs involving 5-aminotetrazole forming a background for further investigations in this area.
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