Journal
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
Volume 46, Issue 5, Pages 400-412Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/10408347.2015.1106932
Keywords
Food and nutrition; metabolomics; natural products; nuclear magnetic spectroscopy; quality control
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Funding
- SERB-DST, New Delhi under the Fast Track Scheme for Young Scientist [SB/YS/LS-81/2014]
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NMR spectroscopy has multidisciplinary applications, including excellent impact in metabolomics. The analytical capacity of NMR spectroscopy provides information for easy qualitative and quantitative assessment of both endogenous and exogenous metabolites present in biological samples. The complexity of a particular metabolite and its contribution in a biological system are critically important for understanding the functional state that governs the organism's phenotypes. This review covers historical aspects of developments in the NMR field, its applications in chemical profiling, metabolomics, and quality control of plants and their derived medicines, foods, and other products. The bottlenecks of NMR in metabolic profiling are also discussed, keeping in view the future scope and further technological interventions.
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