Journal
GREEN CHEMISTRY
Volume 19, Issue 23, Pages 5703-5707Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7gc02097j
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2,3-Dihydro-1,5-benzothiazepines have been obtained through a domino process involving a Michael addition of 2-aminothiophenols to chalcones, followed by in situ cyclization. Up to 98% chemical yields have been obtained at room temperature under essentially neutral conditions by using hexafluoro-2propanol as an efficient medium.
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