Journal
STEM CELL REVIEWS AND REPORTS
Volume 17, Issue 1, Pages 4-8Publisher
SPRINGER
DOI: 10.1007/s12015-020-09987-4
Keywords
SARS-CoV-2; Covid-19; Coagulopathy; D-dimers; Lymphopenia; Mesenchymal stem cells; Cytokine; Inflammation; Thrombosis; Stem cells
Funding
- French research national agency (Agence Nationale pour la Recherche) ANR SARCODO
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SARS-CoV-2 viruses are positive single-stranded RNA viruses that can lead to Covid-19, a respiratory infection with significant impact on the hematopoietic system and hemostasis, causing various cardiovascular complications. The medical community is exploring new treatment approaches for this infection, including targeted anti-inflammatory drugs and stem cell therapies, based on understanding Covid-19 pathophysiology, especially related to hematological disorders.
SARS-CoV-2 viruses are positive single-stranded RNA viruses, whose infection can be asymptomatic or lead to the coronavirus disease 2019 (Covid-19). Covid-19 is a respiratory infection with a significant impact on the hematopoietic system and hemostasis leading to several cardiovascular complications. Hematologic consequences of this new infection allowed medical community to start new treatment approaches concerning infection going from targeted anti-inflammatory drugs to anticoagulation or stem cell therapies. A better understanding of Covid-19 pathophysiology, in particular hematological disorders, will help to choose appropriate treatment strategies.
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