4.6 Article

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

Related references

Note: Only part of the references are listed.
Article Genetics & Heredity

Prediction of CYP2D6 phenotype from genotype across world populations

Andrea Gaedigk et al.

GENETICS IN MEDICINE (2017)

Article Pharmacology & Pharmacy

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update

J. A. Johnson et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)

Article Pharmacology & Pharmacy

High Frequency of CYP2D6 Ultrarapid Metabolizer Genotype in the Finnish Population

Paavo Pietarinen et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2016)

Review Biochemistry & Molecular Biology

The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity

Volker M. Lauschke et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Multidisciplinary Sciences

Analysis of protein-coding genetic variation in 60,706 humans

Monkol Lek et al.

NATURE (2016)

Article Genetics & Heredity

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes

Douglas M. Ruderfer et al.

NATURE GENETICS (2016)

Article Pharmacology & Pharmacy

Requirements for comprehensive pharmacogenetic genotyping platforms

Volker M. Lauschke et al.

PHARMACOGENOMICS (2016)

Editorial Material Pharmacology & Pharmacy

Precision Medicine and Rare Genetic Variants

Volker M. Lauschke et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2016)

Article Multidisciplinary Sciences

A global reference for human genetic variation

David M. Altshuler et al.

NATURE (2015)

Article Genetics & Heredity

Pharmacogenomic information in drug labels: European Medicines Agency perspective

F. Ehmann et al.

PHARMACOGENOMICS JOURNAL (2015)

Article Pharmacology & Pharmacy

CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126☆

Masataka Nakano et al.

DRUG METABOLISM AND DISPOSITION (2015)

Article Medicine, General & Internal

Genotype-Guided vs Clinical Dosing of Warfarin and Its Analogues Meta-analysis of Randomized Clinical Trials

Kathleen Stergiopoulos et al.

JAMA INTERNAL MEDICINE (2014)

Article Pharmacology & Pharmacy

Kinetic Interpretation of the Importance of OATP1B3 and MRP2 in Docetaxel-Induced Hematopoietic Toxicity

A. Yamada et al.

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2014)

Article Genetics & Heredity

Detection of Clinically Relevant Copy Number Variants with Whole-Exome Sequencing

Joep de Ligt et al.

HUMAN MUTATION (2013)

Article Medicine, General & Internal

A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing

Stephen E. Kimmel et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Munir Pirmohamed et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Multidisciplinary Sciences

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

Jacob A. Tennessen et al.

SCIENCE (2012)

Review Genetics & Heredity

Human Copy Number Variation and Complex Genetic Disease

Santhosh Girirajan et al.

ANNUAL REVIEW OF GENETICS, VOL 45 (2011)

Article Biochemistry & Molecular Biology

Global patterns of genetic diversity and signals of natural selection for human ADME genes

Jing Li et al.

HUMAN MOLECULAR GENETICS (2011)

Article Biotechnology & Applied Microbiology

The impact of pharmacogenetics of metabolic enzymes and transporters on the pharmacokinetics of telmisartan in healthy volunteers

Akihiro Yamada et al.

PHARMACOGENETICS AND GENOMICS (2011)

Review Biochemistry & Molecular Biology

Copy number variants in pharmacogenetic genes

Yijing He et al.

TRENDS IN MOLECULAR MEDICINE (2011)

Review Pharmacology & Pharmacy

Impact of OATP transporters on pharmacokinetics

A. Kalliokoski et al.

BRITISH JOURNAL OF PHARMACOLOGY (2009)

Article Biochemistry & Molecular Biology

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia

Serena Sanna et al.

HUMAN MOLECULAR GENETICS (2009)

Article Medicine, General & Internal

Medication use leading to emergency department visits for adverse drug events in older adults

Daniel S. Budnitz et al.

ANNALS OF INTERNAL MEDICINE (2007)

Article Multidisciplinary Sciences

Global variation in copy number in the human genome

Richard Redon et al.

NATURE (2006)

Article Pharmacology & Pharmacy

Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans

Naoki Ishiguro et al.

DRUG METABOLISM AND DISPOSITION (2006)

Article Genetics & Heredity

Common deletion polymorphisms in the human genome

SA McCarroll et al.

NATURE GENETICS (2006)

Article Pharmacology & Pharmacy

Incidence of adverse drug reactions in paediatric in/out-patients: a systematic review and meta-analysis of prospective studies

P Impicciatore et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2001)

Article Biochemistry & Molecular Biology

Clinical application of pharmacogenetics

BB Spear et al.

TRENDS IN MOLECULAR MEDICINE (2001)