4.7 Review

Molecular and cellular mechanisms of liver fibrosis and its regression

Related references

Note: Only part of the references are listed.
Review Gastroenterology & Hepatology

Primary biliary cholangitis: pathogenesis and therapeutic opportunities

Aliya F. Gulamhusein et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

Review Biochemistry & Molecular Biology

Molecular Mechanisms Driving Progression of Liver Cirrhosis towards Hepatocellular Carcinoma in Chronic Hepatitis B and C Infections: A Review

Tatsuo Kanda et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Gastroenterology & Hepatology

Inflammatory pathways in alcoholic steatohepatitis

Bin Gao et al.

JOURNAL OF HEPATOLOGY (2019)

Review Gastroenterology & Hepatology

Neonatal cholestasis: emerging molecular diagnostics and potential novel therapeutics

Amy G. Feldman et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Article Pharmacology & Pharmacy

Inhibition of Human Neutrophil Extracellular Trap (NET) Production by Propofol and Lipid Emulsion

Angela Meier et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Gastroenterology & Hepatology

Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation

Nadine Gehrke et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2018)

Article Cell Biology

The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids

Cholsoon Jang et al.

CELL METABOLISM (2018)

Editorial Material Gastroenterology & Hepatology

Exploring new treatment paradigms for alcoholic hepatitis by extrapolating from NASH and cholestasis

Thoetchai (Bee) Peeraphatdit et al.

JOURNAL OF HEPATOLOGY (2018)

Review Biochemistry & Molecular Biology

Liver fibrosis: Direct antifibrotic agents and targeted therapies

Detlef Schuppan et al.

MATRIX BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Mechanisms of NAFLD development and therapeutic strategies

Scott L. Friedman et al.

NATURE MEDICINE (2018)

Review Gastroenterology & Hepatology

Liver sinusoidal endothelial cells - gatekeepers of hepatic immunity

Shishir Shetty et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)

Article Biochemistry & Molecular Biology

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

Ju Youn Kim et al.

Article Cell Biology

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis

Changyu Zhu et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

Article Gastroenterology & Hepatology

Neutrophils Alleviate Fibrosis in the CCl4-Induced Mouse Chronic Liver Injury Model

Eiko Saijou et al.

HEPATOLOGY COMMUNICATIONS (2018)

Article Gastroenterology & Hepatology

Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis

Katharina Brandl et al.

JOURNAL OF HEPATOLOGY (2018)

Article Hematology

The Role of Plasminogen Activator Inhibitor Type-1 in Fibrosis

Panagiotis Flevaris et al.

SEMINARS IN THROMBOSIS AND HEMOSTASIS (2017)

Article Medicine, Research & Experimental

Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis

Yukinori Koyama et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Gastroenterology & Hepatology

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Auvro R. Mridha et al.

JOURNAL OF HEPATOLOGY (2017)

Article Multidisciplinary Sciences

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shabnam Shalapour et al.

NATURE (2017)

Review Gastroenterology & Hepatology

Mechanisms of hepatic stellate cell activation

Takuma Tsuchida et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)

Article Multidisciplinary Sciences

Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model

Tejas R. Karhadkar et al.

SCIENTIFIC REPORTS (2017)

Review Gastroenterology & Hepatology

Histopathological evaluation of liver fibrosis and cirrhosis regression

Regina C. Lo et al.

CLINICAL AND MOLECULAR HEPATOLOGY (2017)

Review Biochemistry & Molecular Biology

FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases

Junichiro Sonoda et al.

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2017)

Review Immunology

Liver macrophages in tissue homeostasis and disease

Oliver Krenkel et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Letter Substance Abuse

Microbiota and Alcoholic Liver Disease

Peng Chen et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2016)

Review Biochemistry & Molecular Biology

Pathogenesis of nonalcoholic steatohepatitis

Wensheng Liu et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Article Gastroenterology & Hepatology

Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis

Mei Xiang et al.

JOURNAL OF HEPATOLOGY (2016)

Review Cell Biology

TGF-/SMAD Pathway and Its Regulation in Hepatic Fibrosis

Fengyun Xu et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Methylsulfonylmethane inhibits NLRP3 inflammasome activation

Huijeong Ahn et al.

CYTOKINE (2015)

Article Gastroenterology & Hepatology

Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis

Eduardo Vilar-Gomez et al.

GASTROENTEROLOGY (2015)

Article Gastroenterology & Hepatology

Bariatric Surgery Reduces Features of Nonalcoholic Steatohepatitis in Morbidly Obese Patients

Guillaume Lassailly et al.

GASTROENTEROLOGY (2015)

Article Gastroenterology & Hepatology

Pathobiology of liver fibrosis: a translational success story

Youngmin A. Lee et al.

Article Medicine, General & Internal

Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection

J. J. Feld et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, Research & Experimental

Vascular adhesion protein-1 promotes liver inflammation and drives hepatic

Chris J. Weston et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Proceedings Paper Biochemistry & Molecular Biology

Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer

Nasun Hah et al.

21ST CENTURY GENETICS: GENES AT WORK, VOL 80, 2015 (2015)

Article Medicine, Research & Experimental

Hepatic stellate cells contribute to progenitor cells and liver regeneration

Claus Kordes et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Multidisciplinary Sciences

Origin of myofibroblasts in the fibrotic liver in mice

Keiko Iwaisako et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Editorial Material Cell Biology

Inactivation of myofibroblasts during regression of liver fibrosis

Tatiana Kisseleva et al.

CELL CYCLE (2013)

Review Gastroenterology & Hepatology

Pathogenesis of Primary Sclerosing Cholangitis and Advances in Diagnosis and Management

John E. Eaton et al.

GASTROENTEROLOGY (2013)

Article Gastroenterology & Hepatology

Cross-Talk Between Notch and Hedgehog Regulates Hepatic Stellate Cell Fate in Mice

Guanhua Xie et al.

HEPATOLOGY (2013)

Article Gastroenterology & Hepatology

Hepatoprotective and anti-fibrotic functions of interleukin-22: Therapeutic potential for the treatment of alcoholic liver disease

Xiaoni Kong et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013)

Article Biochemistry & Molecular Biology

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

Neil C. Henderson et al.

NATURE MEDICINE (2013)

Article Gastroenterology & Hepatology

The global NAFLD epidemic

Rohit Loomba et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)

Review Endocrinology & Metabolism

Non-alcoholic steatohepatitis: a microbiota-driven disease

Alexander R. Moschen et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2013)

Editorial Material Pharmacology & Pharmacy

Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease?

Ning Ding et al.

EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2013)

Article Gastroenterology & Hepatology

Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

Virginia Hernandez-Gea et al.

GASTROENTEROLOGY (2012)

Article Gastroenterology & Hepatology

Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice

Juliane S. Troeger et al.

GASTROENTEROLOGY (2012)

Review Gastroenterology & Hepatology

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

Hashem B. El-Serag

GASTROENTEROLOGY (2012)

Article Medicine, Research & Experimental

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

Jan Petrasek et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Review Genetics & Heredity

Genetic variants in candidate genes influencing NAFLD progression

Michelino Di Rosa et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2012)

Review Neurosciences

Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut

Ekihiro Seki et al.

JOURNAL OF PHYSIOLOGY-LONDON (2012)

Article Medicine, Research & Experimental

Reversal of liver fibrosis by the antagonism of endocannabinoid CB1 receptor in a rat model of CCl4-induced advanced cirrhosis

Ferdinando A. Giannone et al.

LABORATORY INVESTIGATION (2012)

Review Biotechnology & Applied Microbiology

Targeting the TGFβ signalling pathway in disease

Rosemary J. Akhurst et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Article Multidisciplinary Sciences

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

Keiko Iwaisako et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

Tatiana Kisseleva et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

Prakash Ramachandran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Cell Biology

Overview of the Matrisome-An Inventory of Extracellular Matrix Constituents and Functions

Richard O. Hynes et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

Article Pathology

Migration of Fibrocytes in Fibrogenic Liver Injury

David Scholten et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

Review Immunology

Role of IL-17 and Th17 Cells in Liver Diseases

Linda Hammerich et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2011)

Article Gastroenterology & Hepatology

The Effects of Angiotensin Blocking Agents on the Progression of Liver Fibrosis in the HALT-C Trial Cohort

Barham K. Abu Dayyeh et al.

DIGESTIVE DISEASES AND SCIENCES (2011)

Review Pharmacology & Pharmacy

Lysophosphatidic acid-1-receptor targeting agents for fibrosis

Chloe Rancoule et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2011)

Review Gastroenterology & Hepatology

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

Bin Gao et al.

GASTROENTEROLOGY (2011)

Review Immunology

The inflammasome: an integrated view

Olaf Gross et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Gastroenterology & Hepatology

CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice

Sachiko Ishikawa et al.

JOURNAL OF HEPATOLOGY (2011)

Review Gastroenterology & Hepatology

The role of thiazolidinediones in non-alcoholic steatohepatitis - A systematic review and meta analysis

Suzanne E. Mahady et al.

JOURNAL OF HEPATOLOGY (2011)

Article Genetics & Heredity

Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection

Tatiana Kisseleva et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2011)

Article Gastroenterology & Hepatology

IκB kinase-beta inhibitor attenuates hepatic fibrosis in mice

Jue Wei et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2011)

Article Gastroenterology & Hepatology

Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis

Yury Popov et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)

Review Biochemistry & Molecular Biology

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

Keith Brew et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)

Review Biochemistry & Molecular Biology

The Inflammasomes

Kate Schroder et al.

Article Gastroenterology & Hepatology

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

Kouichi Miura et al.

GASTROENTEROLOGY (2010)

Article Gastroenterology & Hepatology

MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis

Jelena Mann et al.

GASTROENTEROLOGY (2010)

Review Gastroenterology & Hepatology

Portal Fibroblasts: Underappreciated Mediators of Biliary Fibrosis

Jonathan A. Dranoff et al.

HEPATOLOGY (2010)

Review Gastroenterology & Hepatology

Alcoholic Liver Disease

Robert S. O'Shea et al.

HEPATOLOGY (2010)

Article Gastroenterology & Hepatology

Hepatocytes Do Not Undergo Epithelial-Mesenchymal Transition in Liver Fibrosis in Mice

Kojiro Taura et al.

HEPATOLOGY (2010)

Article Biochemistry & Molecular Biology

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment

Vivian Barry-Hamilton et al.

NATURE MEDICINE (2010)

Article Medicine, General & Internal

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis.

Arun J. Sanyal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Multidisciplinary Sciences

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

Kate Schroder et al.

SCIENCE (2010)

Review Gastroenterology & Hepatology

Nuclear Receptor Regulation of the Adaptive Response of Bile Acid Transporters in Cholestasis

Martin Wagner et al.

SEMINARS IN LIVER DISEASE (2010)

Review Immunology

The impact of the extracellular matrix on inflammation

Lydia Sorokin

NATURE REVIEWS IMMUNOLOGY (2010)

Review Oncology

SENESCENCE Senescence in tumours: evidence from mice and humans

Manuel Collado et al.

NATURE REVIEWS CANCER (2010)

Article Gastroenterology & Hepatology

Inflammasome-mediated regulation of hepatic stellate cells

Azuma Watanabe et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)

Article Gastroenterology & Hepatology

Cholestasis and cholestatic syndromes

Gideon M. Hirschfield et al.

CURRENT OPINION IN GASTROENTEROLOGY (2009)

Article Gastroenterology & Hepatology

Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I-II clinical trial

Pedram Kharaziha et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2009)

Editorial Material Gastroenterology & Hepatology

The Bone Marrow and Liver Fibrosis: Friend or Foe?

Yiannis N. Kallis et al.

GASTROENTEROLOGY (2009)

Article Gastroenterology & Hepatology

The Interleukin-17 Pathway Is Involved in Human Alcoholic Liver Disease

Arnaud Lemmers et al.

HEPATOLOGY (2009)

Article Gastroenterology & Hepatology

Hepatic Recruitment of the Inflammatory Gr1+ Monocyte Subset Upon Liver Injury Promotes Hepatic Fibrosis

Karlin Raja Karlmark et al.

HEPATOLOGY (2009)

Article Gastroenterology & Hepatology

CCR2 Promotes Hepatic Fibrosis in Mice

Ekihiro Seki et al.

HEPATOLOGY (2009)

Article Cell Biology

Thy-1 is expressed in myofibroblasts but not found in hepatic stellate cells following liver injury

Jozsef Dudas et al.

HISTOCHEMISTRY AND CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Hyaluronan Orchestrates Transforming Growth Factor-β1-dependent Maintenance of Myofibroblast Phenotype

Jason Webber et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Cell Biology

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

Mohamed Lamkanfi et al.

JOURNAL OF CELL BIOLOGY (2009)

Review Medicine, Research & Experimental

EMT: When epithelial cells decide to become mesenchymal-like cells

Raghu Kalluri

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Immunology

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

Piero Vavassori et al.

JOURNAL OF IMMUNOLOGY (2009)

Review Genetics & Heredity

Molecular mechanisms involved in NAFLD progression

Mariano Malaguarnera et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2009)

Review Medicine, General & Internal

MEDICAL PROGRESS Alcoholic Hepatitis

Michael R. Lucey et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Review Multidisciplinary Sciences

The Extracellular Matrix: Not Just Pretty Fibrils

Richard O. Hynes

SCIENCE (2009)

Review Gastroenterology & Hepatology

Reversibility of liver fibrosis

Prakash Ramachandran et al.

ANNALS OF HEPATOLOGY (2009)

Article Oncology

Epithelial-Mesenchymal Transition

Jiri Zavadil et al.

CANCER RESEARCH (2008)

Article Biochemistry & Molecular Biology

Senescence of activated stellate cells limits liver fibrosis

Valery Krizhanovsky et al.

Review Medicine, Research & Experimental

Mechanisms of fibrogenesis

Tatiana Kisseleva et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2008)

Review Gastroenterology & Hepatology

Mechanisms of hepatic fibrogenesis

Scott L. Friedman

GASTROENTEROLOGY (2008)

Article Gastroenterology & Hepatology

Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence

Laurie D. DeLeve et al.

HEPATOLOGY (2008)

Review Gastroenterology & Hepatology

The role of matrix stiffness in regulating cell behavior

Rebecca G. Wells

HEPATOLOGY (2008)

Article Gastroenterology & Hepatology

Inhibition of plasminogen activator inhibitor-1 expression by siRNA in rat hepatic stellate cells

Ping-Fang Hu et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2008)

Article Biochemistry & Molecular Biology

TLR4 enhances TGF-β signaling and hepatic fibrosis

Ekihiro Seki et al.

NATURE MEDICINE (2007)

Article Immunology

Reduction of bleomycin-induced pulmonary fibrosis by serum amyloid P

Darrell Pilling et al.

JOURNAL OF IMMUNOLOGY (2007)

Article Biochemistry & Molecular Biology

Involvement of hyaluronan in regulation of fibroblast phenotype

Soma Meran et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

Elisabeth M. Zeisberg et al.

NATURE MEDICINE (2007)

Article Multidisciplinary Sciences

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

Daniel Mucida et al.

SCIENCE (2007)

Review Medicine, Research & Experimental

The role of CXC chemokines in pulmonary fibrosis

Robert M. Strieter et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Review Medicine, Research & Experimental

Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

John P. Iredale

JOURNAL OF CLINICAL INVESTIGATION (2007)

Review Cell Biology

Fibrocytes in lung disease

Brigitte N. Gomperts et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2007)

Article Gastroenterology & Hepatology

Blockade of renin-angiotensin system in antifibrotic therapy

Hitoshi Yoshiji et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2007)

Review Biochemistry & Molecular Biology

Renin-angiotensin system inhibitors as therapeutic alternatives in the treatment of chronic liver diseases

Hitoshi Yoshiji et al.

CURRENT MEDICINAL CHEMISTRY (2007)

Article Gastroenterology & Hepatology

Hepatic stellate cells and the reversal of fibrosis

Tatiana Kisseleva et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Gastroenterology & Hepatology

Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis

Tatiana Kisseleva et al.

JOURNAL OF HEPATOLOGY (2006)

Article Gastroenterology & Hepatology

Loss of MMP 13 attenuates murine hepatic injury and fibrosis during Cholestasis

Hiroshi Uchinami et al.

HEPATOLOGY (2006)

Article Gastroenterology & Hepatology

The bone marrow functionally contributes to liver fibrosis

Francesco P. Russo et al.

GASTROENTEROLOGY (2006)

Article Pediatrics

A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000

Benjamin L. Shneider et al.

JOURNAL OF PEDIATRICS (2006)

Review Gastroenterology & Hepatology

Hematopoietic cells as hepatocyte stem cells: A critical review of the evidence

SS Thorgeirsson et al.

HEPATOLOGY (2006)

Article Immunology

TGF-β and Smad3 signaling link inflammation to chronic fibrogenesis

P Bonniaud et al.

JOURNAL OF IMMUNOLOGY (2005)

Review Biochemistry & Molecular Biology

A protein canyon in the FGF-FGF receptor dimer selects from an a la carte menu of heparan sulfate motifs

M Mohammadi et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2005)

Article Gastroenterology & Hepatology

Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice

L Yang et al.

JOURNAL OF HEPATOLOGY (2005)

Article Gastroenterology & Hepatology

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

DE Kleiner et al.

HEPATOLOGY (2005)

Article Pharmacology & Pharmacy

Inhibition of TGF-β signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis

AC de Gouville et al.

BRITISH JOURNAL OF PHARMACOLOGY (2005)

Article Gastroenterology & Hepatology

The role of matrix stiffness in hepatic stellate cell activation and liver fibrosis

RG Wells

JOURNAL OF CLINICAL GASTROENTEROLOGY (2005)

Article Biochemistry & Molecular Biology

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

F Geissmann et al.

PLOS BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Adipogenic transcriptional regulation of hepatic stellate cells

HY She et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Chemistry, Medicinal

Caspase inhibitors: A pharmaceutical industry perspective

SD Linton

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)

Article Medicine, Research & Experimental

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

JS Duffield et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Biochemistry & Molecular Biology

Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow

L Song et al.

FASEB JOURNAL (2004)

Review Biochemistry & Molecular Biology

Circulating fibrocytes: collagen-secreting cells of the peripheral blood

TE Quan et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Gastroenterology & Hepatology

A significant proportion of myofibroblasts are of bone marrow origin in human liver fibrosis

SJ Forbes et al.

GASTROENTEROLOGY (2004)

Article Gastroenterology & Hepatology

Decreased fibrosis during corticosteroid therapy of autoimmune hepatitis

AJ Czaja et al.

JOURNAL OF HEPATOLOGY (2004)

Article Biochemistry & Molecular Biology

Peroxisome proliferator-activated receptor γ induces a phenotypic switch from activated to quiescent hepatic stellate cells

S Hazra et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

Neutrophil extracellular traps kill bacteria

V Brinkmann et al.

SCIENCE (2004)

Article Pharmacology & Pharmacy

The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse

A Canbay et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Article Gastroenterology & Hepatology

Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation

LD DeLeve et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)

Article Medicine, Research & Experimental

Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis

RJ Phillips et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Article Medicine, Research & Experimental

Bone marrow-derived progenitor cells in pulmonary fibrosis

N Hashimoto et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Review Immunology

Interleukin-17 family members and inflammation

JK Kolls et al.

IMMUNITY (2004)

Review Medicine, Research & Experimental

Epithelial-mesenchymal transition and its implications for fibrosis

R Kalluri et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Review Biochemistry & Molecular Biology

Mechanisms of TGF-β signaling from cell membrane to the nucleus

YG Shi et al.

Review Gastroenterology & Hepatology

Liver fibrosis - from bench to bedside

SL Friedman

JOURNAL OF HEPATOLOGY (2003)

Review Gastroenterology & Hepatology

Hepatic stellate cell behavior during resolution of liver injury

JP Iredale

SEMINARS IN LIVER DISEASE (2001)

Review Gastroenterology & Hepatology

History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells

A Geerts

SEMINARS IN LIVER DISEASE (2001)

Article Gastroenterology & Hepatology

The role of Smad3 in mediating mouse hepatic stellate cell activation

B Schnabl et al.

HEPATOLOGY (2001)

Article Multidisciplinary Sciences

Genetic programs of epithelial cell plasticity directed by transforming growth factor-β

J Zavadil et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Gastroenterology & Hepatology

New aspects of hepatic fibrosis

DA Brenner et al.

JOURNAL OF HEPATOLOGY (2000)