4.7 Review

Biologically active indolizidine alkaloids

Journal

MEDICINAL RESEARCH REVIEWS
Volume 41, Issue 2, Pages 928-960

Publisher

WILEY
DOI: 10.1002/med.21747

Keywords

biological activity; indolizidine alkaloids; natural products; pharmacological effects

Funding

  1. National Natural Science Foundation of China [21672092, 31371975]
  2. National Key Research and Development Program of China [2017YFD0201404]
  3. Key Program for International S&T Cooperation Projects of China Gansu Province [18YF1WA115]

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Indolizidine alkaloids are chemical constituents isolated from various plants and animals, with important biological activities. Studying the biological activity and pharmacological effects of these alkaloids can lead to the discovery of new drugs.
Indolizidine alkaloids are chemical constituents isolated from various marine and terrestrial plants and animals, including but not limited to trees, fungi, ants, and frogs, with a myriad of important biological activities. In this review, we discuss the biological activity and pharmacological effects of indolizidine alkaloids and offer new avenues toward the discovery of new and better drugs based on these naturally occurring compounds.

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