4.7 Article

Drinking water pollutants may affect the immune system: concerns regarding COVID-19 health effects

Journal

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
Volume 28, Issue 1, Pages 1235-1246

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11356-020-11487-4

Keywords

SARS-CoV-2; Immune response; Cytokines; PFAS; plastic components and plasticizers; Metals

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The current coronavirus pandemic is causing significant impacts and changes to our way of life. While the mechanisms of the COVID-19 virus are still being researched, there is evidence of its effects on the immune system, leading to respiratory distress. Major contaminants in drinking water may exacerbate COVID-19 respiratory symptoms, posing a threat to those exposed to the virus.
The current coronavirus pandemic is leading to significant impacts on the planet, changing our way of life. Although the COVID-19 virus mechanisms of action and pathogenesis are still under extensive research, immune system effects are evident, leading, in many cases, to respiratory distress. Although apparent pollution reduction has been noticed by the population, environmental and human health impacts due to the increased use of plastic waste and disinfectants is concerning. One of the main routes of human exposure to pollutants is through drinking water. Thus, this point of view discusses some major contaminants in drinking water known to be immunotoxic, exploring sources and drinking water routes and emphasizing the known mechanisms of action that could likely compromise the effective immune response of humans, particularly raising concerns regarding people exposed to the COVID-19 virus. Based on a literature review, metals, plastic components, plasticizers, and per- and polyfluoroalkyl substances may display the potential to exacerbate COVID-19 respiratory symptoms, although epidemiological studies are still required to confirm the synergistic effects between these pollutants and the virus.

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