Journal
PHARMACOECONOMICS
Volume 39, Issue 6, Pages 627-630Publisher
ADIS INT LTD
DOI: 10.1007/s40273-020-00972-w
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Funding
- University of California, Los Angeles (UCLA), Resource Centers for Minority Aging Research Center for Health Improvement of Minority Elderly (RCMAR/CHIME) under NIH/NIA [P30-AG021684]
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This study emphasizes the importance of recognizing the overlap between depressive symptoms and HRQOL measures in research models to draw more accurate conclusions. Acknowledging this overlap will lead to better understanding of the prognostic value of depression and other HRQOL measures for various health outcomes.
Because depressive symptoms are a part of health-related quality-of-life (HRQOL) measures, measures of depression will be empirically associated with HRQOL. We discuss examples of published research where authors ignored or did not fully account for overlap between depressive symptom and HRQOL measures. Future researchers need to recognize when their models include conceptually similar variables on the same side or both sides of the equation. This awareness will lead to more accurate conclusions about the prognostic value of depression and other HRQOL measures for health care utilization, mortality, and other outcomes. It will also result in fewer incorrect claims about the effect of depression on HRQOL.
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