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Two-dimensional metal organic frameworks for biomedical applications

Publisher

WILEY
DOI: 10.1002/wnan.1674

Keywords

bioimaging; biosensing; drug delivery; metal organic frameworks (MOFs); tissue engineering

Funding

  1. Department of Science and Technology (DST) [IUSSTF/JC-025/2016, SR/WOS-A/CS-17/2017]
  2. Indo-US Science & Technology Forum (IUSSTF), India [IUSSTF/JC-025/2016]
  3. National Institute of Biomedical Imaging and Bioengineering (NIBIB) [DP2 EB026265]
  4. National Science Foundation [CBET 1705852]
  5. Office of the President at Texas AM University

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Two-dimensional (2D) metal organic frameworks (MOFs) are emerging layered nanomaterials with defined structure and composition, showing potential for various biomedical applications.
Two-dimensional (2D) metal organic frameworks (MOFs), are an emerging class of layered nanomaterials with well-defined structure and modular composition. The unique pore structure, high flexibility, tunability, and ability to introduce desired functionality within the structural framework, have led to potential use of MOFs in biomedical applications. This article critically reviews the application of 2D MOFs for therapeutic delivery, tissue engineering, bioimaging, and biosensing. Further, discussion on the challenges and strategies in next generation of 2D MOFs are also included. This article is categorized under: Nanotechnology Approaches to Biology > Nanoscale Systems in Biology

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