Large vessel vasculitis: imaging standards of 18F-FDG PET/CT

Improvements in positron emission tomography (PET) technology have contributed to increased diagnostic accuracy in patients with large-vessel vasculitis (LVV) over the last decades. Many systematic reviews and meta-analyses were conducted, and earlier diagnosis by F-18-FDG PET can be made in patients suspected of having LVV. Two subtypes, Takayasu arteritis and giant cell arteritis, will progress when poorly responding to corticosteroids and augmented immunosuppression. In most patients, disease activity cannot be monitored by laboratory tests alone; therefore, glucose metabolism may be a source for possible biomarkers. In this review, we present current concepts regarding F-18-FDG PET/CT imaging standards.

Automated summary

Advances in PET technology have enhanced diagnostic accuracy for LVV patients, with F-18-FDG PET enabling early diagnosis. Takayasu arteritis and giant cell arteritis may require augmented immunosuppression for treatment.