Journal
PROBIOTICS AND ANTIMICROBIAL PROTEINS
Volume 13, Issue 3, Pages 734-738Publisher
SPRINGER
DOI: 10.1007/s12602-020-09719-7
Keywords
Otitis media; Recurrent otitis media; Otitis media pathogens; Probiotics; S; salivarius BLIS K12; In vitro inhibition
Categories
Funding
- Paediatric Department, University of Otago, Christchurch
Ask authors/readers for more resources
This study assessed the in vitro inhibitory activity of Streptococcus salivarius BLIS K12 against otitis media pathogens, showing that 48% of isolates were inhibited by S. salivarius BLIS K12. This bacteriocin is effective in inhibiting the growth of the most common otitis media pathogens.
Otitis media is a common childhood infection, frequently requiring antibiotics. With high rates of antibiotic prescribing and increasing antibiotic resistance, new strategies in otitis media prevention and treatment are needed. The aim of this study was to assess the in vitro inhibitory activity Streptococcus salivarius BLIS K12 against otitis media pathogens. Efficacy of the bacteriocin activity of S. salivarius BLIS K12 against the otitis media isolates was assessed using the deferred antagonism test. Overall, 48% of pathogenic isolates exhibited some growth inhibition by S. salivarius BLIS K12. S. salivarius BLIS K12 can inhibit the in vitro growth of the most common pathogens.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available