Recent Advancement of Synthesis of Isatins as a Versatile Pharmacophore: A review

Isatin (1 H-indole-2, 3-Dione) and its derivatives are versatile compounds which acts as a precursor for a large number of pharmacologically active compounds. Therefore isatins have a significant importance in the synthesis of different heterocyclic compounds. Isatins show variety of biological activities. In this review we focus on synthetic methods of isatins and their biological activities such as antimicrobial, anticonvulsant, anti-inflammatory and analgesic activity, antitubercular activity.

Automated summary

Isatin and its derivatives are versatile compounds acting as precursors for various pharmacologically active substances. They exhibit a variety of biological activities, including antimicrobial, anticonvulsant, anti-inflammatory, analgesic, and antitubercular activities.