Journal
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
Volume 15, Issue 1, Pages 23-31Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.dsx.2020.11.004
Keywords
Fasting plasma glucose; Insulin; Hemoglobin A1c; HOMA-IR; Green tea; Type 2 diabetes; meta-Analysis
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This study conducted a systematic review and meta-analysis on the potential effects of supplementary intake of green tea in patients with type 2 diabetes mellitus, and found that it had no significant impact on fasting plasma glucose, fasting insulin, hemoglobin A1c, and HOMA-IR.
Background and aims: Several studies have investigated the potential beneficial effects of green tea in patients with type 2 diabetes mellitus (T2DM). Therefore, we aimed to perform a systematic review and meta-analysis of the randomized controlled trials (RCTs) that assessed the effect of supplementary intake of green tea on fasting plasma glucose (FPG), fasting insulin, hemoglobin A1c (HbA1c) and HOMA-IR in patients with T2DM. Methods: A systematic search was performed in Web of Science, PubMed and Scopus without any language and time restriction up to June 2019, to retrieve the related RCTs. Meta-analysis was carried out using both the random and fixed effects model where appropriate. I2 index was used to evaluate the heterogeneity. Results: Initial search yielded 780 publications. Fourteen articles were eligible. Our meta-analysis indicated that the supplementary intake of green tea had no significant effect on FPG, fasting insulin, HbA1c and HOMA-IR in patients with T2DM. Conclusion: Results of the present systematic review and meta-analysis indicated that the supplementary intake of green tea had no significant effect on FPG, fasting insulin, HbA1c and HOMA-IR in patients with T2DM. (C) 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.
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