Atypical optic neuritis: An overview

Optic neuritis (ON) refers to conditions that involve inflammation of the optic nerve. Various autoantibodies have been found, which are associated with central nervous system inflammatory disorders and have provided much information about the immune targets and mechanisms that impact the prognosis, treatment, and recurrence of atypical ON. Therefore, neurologists and ophthalmologists together should work to find out clinical, laboratory, and imaging findings that may provide important clues to the etiology of atypical ON and its management. Various biomarkers have been identified to confirm and distinguish atypical optic neuritis from others. The purpose of this review is to present the current scenario of atypical ON and its clinical management.

Automated summary

Optic neuritis involves inflammation of the optic nerve. Various autoantibodies associated with central nervous system inflammatory disorders provide information that impacts the prognosis, treatment, and recurrence of atypical ON. Collaborative efforts between neurologists and ophthalmologists are essential to finding important clues for the etiology and management of atypical ON. Various biomarkers have been identified to confirm and distinguish atypical optic neuritis from others.