The Affect of Gadolinium Ion on Micelles and Reverse Micelles by NMR Spectroscopy

Paramagnetic gadolinium ions are used as one of the possible contrast agents for magnetic resonance imaging. Contrast agents interact with living cells. An interesting task is to determine how the interaction between the contrast medium and the living cell occurs. The paper presents the results of a study of the interaction between paramagnetic gadolinium ions and membrane models using micelles based on dodecylphosphocholine and reverse micelles based on dioctyl sulfosuccinate sodium salt by nuclear magnetic resonance spectroscopy. From the spectra analysis, it was revealed that the interaction exists for both types of micelles. It is also suggested at a qualitative level the possible site of interaction between gadolinium ions and the hydrophilic part of the bipolar molecules that form micelles.

Automated summary

This study investigates the interaction between paramagnetic gadolinium ions and membrane models using micelles, revealing the existence of interaction for both types of micelles and providing a qualitative suggestion of the possible site of interaction between gadolinium ions and the hydrophilic part of the bipolar molecules that form the micelles.