Journal
JOURNAL OF CANCER
Volume 12, Issue 4, Pages 1154-1160Publisher
IVYSPRING INT PUBL
DOI: 10.7150/jca.51537
Keywords
Photodynamic therapy; lung cancer; inoperable cancer; cancer treatment
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Lung cancer is a leading cause of cancer-related deaths worldwide, with photodynamic therapy (PDT) showing promise as an effective treatment option. Clinical studies have demonstrated that PDT can prolong survival in inoperable cases.
Lung cancer is one of the leading causes of cancer-related death worldwide, with nearly 1.8 million-diagnosis and 1.59 million deaths. Surgery, radiotherapy, and chemotherapy in individual or combination are commonly used to treat lung cancers. Photodynamic therapy (PDT) is a highly selective method for the destruction of cancer cells by exerting cytotoxic activity on malignant cells. PDT has been the subject of numerous clinical studies and has proven to be an effective strategy for cancer therapy. Clinical studies revealed that PDT could prolong survival in patients with inoperable cancers and significantly improve quality of life. For inoperable lung cancer cases, PDT could be an effective therapy. Despite the clinical success reported, PDT is still currently underutilized to treat lung cancer and other tumors. PTD is still a new treatment approach for lung cancer mainly due to the lack of enough clinical research evaluating its' effectiveness and side effects. In this review, we discuss the current prospects and future potentials of PDT in lung cancer treatment.
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