Related references
Note: Only part of the references are listed.In search of definitions: Cancer-associated fibroblasts and their markers
Martin Nurmik et al.
INTERNATIONAL JOURNAL OF CANCER (2020)
Bone-marrow-derived cell-released extracellular vesicle miR-92a regulates hepatic pre-metastatic niche in lung cancer
Ya-Ling Hsu et al.
ONCOGENE (2020)
Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells
Ran Cheng et al.
ONCOGENE (2020)
Impact of breast cancer cells' secretome on the brain metastatic niche remodeling
R. Carvalho et al.
SEMINARS IN CANCER BIOLOGY (2020)
Nanosponges of circulating tumor-derived exosomes for breast cancer metastasis inhibition
Hao Ye et al.
BIOMATERIALS (2020)
Phase I dose-escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer
Takaaki Masuda et al.
CANCER SCIENCE (2020)
Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer
Anders Etzerodt et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Therapeutic Targeting of Vasculature in the Premetastatic and Metastatic Niches Reduces Lung Metastasis
Shanawaz M. Ghouse et al.
JOURNAL OF IMMUNOLOGY (2020)
Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches
Gagan Deep et al.
MOLECULAR CARCINOGENESIS (2020)
Self-Delivery Micellar Nanoparticles Prevent Premetastatic Niche Formation by Interfering with the Early Recruitment and Vascular Destruction of Granulocytic Myeloid-Derived Suppressor Cells
Yang Long et al.
NANO LETTERS (2020)
Epigenetic therapy inhibits metastases by disrupting premetastatic niches
Zhihao Lu et al.
NATURE (2020)
Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
Qing Ji et al.
NATURE COMMUNICATIONS (2020)
Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment
Braeden Medeiros et al.
CANCERS (2020)
Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy
Bo He et al.
CELL REPORTS (2020)
Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice
Milena Armacki et al.
GASTROENTEROLOGY (2020)
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
Alvaro Teijeira et al.
IMMUNITY (2020)
The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites
Sarah Libring et al.
CANCERS (2020)
DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25
Linbin Yang et al.
NATURE (2020)
Isolation and characterization of exosomes for cancer research
Le Zhu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Molecular principles of metastasis: a hallmark of cancer revisited
Jawad Fares et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Tumour heterogeneity and the evolutionary trade-offs of cancer
Jean Hausser et al.
NATURE REVIEWS CANCER (2020)
The blood-brain barrier and blood-tumour barrier in brain tumours and metastases
Costas D. Arvanitis et al.
NATURE REVIEWS CANCER (2020)
Colorectal cancer exosomes induce lymphatic network remodeling in lymph nodes
Bo Sun et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Effects of exosomes on pre-metastatic niche formation in tumors
Yaxin Guo et al.
MOLECULAR CANCER (2019)
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche
Ilaria Elia et al.
NATURE (2019)
Hepatocytes direct the formation of a pro-metastatic niche in the liver
Jae W. Lee et al.
NATURE (2019)
Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer
Ivy X. Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The extracellular matrix in tumor progression and metastasis
Johannes A. Eble et al.
CLINICAL & EXPERIMENTAL METASTASIS (2019)
The Extracellular Matrix Modulates the Metastatic Journey
FuiBoon Kai et al.
DEVELOPMENTAL CELL (2019)
Metastasis Organotropism: Redefining the Congenial Soil
Yang Gao et al.
DEVELOPMENTAL CELL (2019)
Exosome-Mediated Metastasis: Communication from a Distance
Inbal Wortzel et al.
DEVELOPMENTAL CELL (2019)
Macrophages-Triggered Sequential Remodeling of Endothelium-Interstitial Matrix to Form Pre-Metastatic Niche in Microfluidic Tumor Microenvironment
Hyunho Kim et al.
ADVANCED SCIENCE (2019)
Interactions in the (Pre)metastatic Niche Support Metastasis Formation
Ginevra Doglioni et al.
FRONTIERS IN ONCOLOGY (2019)
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer
Yan Wang et al.
STEM CELL RESEARCH & THERAPY (2019)
Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer
Jiangang Zhao et al.
CANCERS (2019)
Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
Rene Jackstadt et al.
CANCER CELL (2019)
Primary prostate cancer educates bone stroma through exosomal pyruvate kinase M2 to promote bone metastasis
Jinlu Dai et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Cancer-associated fibroblasts: an emerging target of anti-cancer immunotherapy
Tongyan Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
The role of collagen in cancer: from bench to bedside
Shuaishuai Xu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
Exosomes promote pre-metastatic niche formation in ovarian cancer
Wenlong Feng et al.
MOLECULAR CANCER (2019)
Metastatic-niche labelling reveals parenchymal cells with stem features
Luigi Ombrato et al.
NATURE (2019)
The Dark Side of Fibroblasts: Cancer-Associated Fibroblasts as Mediators of Immunosuppression in the Tumor Microenvironment
Lea Monteran et al.
FRONTIERS IN IMMUNOLOGY (2019)
Extracellular Matrix Alterations in Metastatic Processes
Mayra Paolillo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1
Yujun Tang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis
Goncalo Rodrigues et al.
NATURE CELL BIOLOGY (2019)
The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasis
Ricardo Romero-Moreno et al.
NATURE COMMUNICATIONS (2019)
An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles
Angelica Ortiz et al.
CANCER CELL (2019)
Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum
WonJae Lee et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models
Ioanna Keklikoglou et al.
NATURE CELL BIOLOGY (2019)
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
Patrick Carlson et al.
NATURE CELL BIOLOGY (2019)
Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG
Yan Gu et al.
NATURE MEDICINE (2019)
Turning foes to friends: targeting cancer-associated fibroblasts
Xueman Chen et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation
Irena Kaplanov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts
Jing Kong et al.
MOLECULAR CANCER (2019)
Brain metastases
Achal Singh Achrol et al.
NATURE REVIEWS DISEASE PRIMERS (2019)
Bone Metastasis: Find Your Niche and Fit in
Weijie Zhang et al.
TRENDS IN CANCER (2019)
Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53
Maximiliane Schuldner et al.
THERANOSTICS (2019)
Neutrophils, G-CSF and their contribution to breast cancer metastasis
Kellie A. Mouchemore et al.
FEBS JOURNAL (2018)
An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential
Liqin Wang et al.
CELL (2018)
As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
Natalya N. Pavlova et al.
CELL METABOLISM (2018)
Asparagine and Glutamine: Co-conspirators Fueling Metastasis
Ming Luo et al.
CELL METABOLISM (2018)
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis
Pengcheng Bu et al.
CELL METABOLISM (2018)
Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer
Maximilian Reichert et al.
DEVELOPMENTAL CELL (2018)
Mesenchymal Stromal Cells: Emerging Roles in Bone Metastasis
Nicola Graham et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Matrix stiffness-upregulated LOXL2 promotes fibronectin production, MMP9 and CXCL12 expression and BMDCs recruitment to assist pre-metastatic niche formation
Sifan Wu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
The biology and role of CD44 in cancer progression: therapeutic implications
Chen Chen et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer
Sylwia Gawrzak et al.
NATURE CELL BIOLOGY (2018)
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization
Ekrem Emrah Er et al.
NATURE CELL BIOLOGY (2018)
Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases
Arnaud Pommier et al.
SCIENCE (2018)
Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer
Tian Fang et al.
NATURE COMMUNICATIONS (2018)
Colorectal cancer-derived small extracellular vesicles establish an inflammatory premetastatic niche in liver metastasis
Yingkuan Shao et al.
CARCINOGENESIS (2018)
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Gang Chen et al.
NATURE (2018)
Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer
Tyler Risom et al.
NATURE COMMUNICATIONS (2018)
Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment
Shin La Shu et al.
SCIENTIFIC REPORTS (2018)
Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer
Davide Melisi et al.
BRITISH JOURNAL OF CANCER (2018)
Understanding the Bone in Cancer Metastasis
Jaime Fornetti et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2018)
Unique pattern of neutrophil migration and function during tumor progression
Sima Patel et al.
NATURE IMMUNOLOGY (2018)
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
Xavier Michelet et al.
NATURE IMMUNOLOGY (2018)
Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels
David Novo et al.
NATURE COMMUNICATIONS (2018)
Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis
Zhicheng Zeng et al.
NATURE COMMUNICATIONS (2018)
Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix
A. E. Yuzhalin et al.
NATURE COMMUNICATIONS (2018)
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice
Jean Albrengues et al.
SCIENCE (2018)
Tissue Specific Origin, Development, and Pathological Perspectives of Pericytes
Tomoko Yamazaki et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2018)
Neutrophils Promote Hepatic Metastasis Growth Through Fibroblast Growth Factor 2-Dependent Angiogenesis in Mice
Alex N. Gordon-Weeks et al.
HEPATOLOGY (2017)
Recruited monocytic myeloid-derived suppressor cells promote the arrest of tumor cells in the premetastatic niche through an IL-1β-mediated increase in E-selectin expression
Huifang Shi et al.
INTERNATIONAL JOURNAL OF CANCER (2017)
New MSC: MSCs as Pericytes Are Sentinels and Gatekeepers
Arnold I. Caplan
JOURNAL OF ORTHOPAEDIC RESEARCH (2017)
Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis
Nao Nishida-Aoki et al.
MOLECULAR THERAPY (2017)
Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine
David Olmeda et al.
NATURE (2017)
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
Matthew J. Hangauer et al.
NATURE (2017)
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
Meera Murgai et al.
NATURE MEDICINE (2017)
S100A7: from mechanism to cancer therapy
L. Padilla et al.
ONCOGENE (2017)
CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis
X. W. Chen et al.
ONCOGENE (2017)
STAT3 activation in endothelial cells is important for tumor metastasis via increased cell adhesion molecule expression
K-J Kim et al.
ONCOGENE (2017)
A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second-Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma
J. Randolph Hecht et al.
ONCOLOGIST (2017)
A Phase II Randomized, Double-Blind, Placebo-Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First-Line Treatment of Pancreatic Adenocarcinoma
Al B. Benson et al.
ONCOLOGIST (2017)
Exosomes: Key mediators of metastasis and pre-metastatic niche formation
Richard J. Lobb et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)
Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis
Haiyang Zhang et al.
NATURE COMMUNICATIONS (2017)
Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche
Michael P. Plebanek et al.
NATURE COMMUNICATIONS (2017)
The regulation of pre-metastatic niche formation by neutrophils
Jadwiga Jablonska et al.
ONCOTARGET (2017)
Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat; a phase 2 consortium/stand Up 2 cancer study
Nilofer S. Azad et al.
ONCOTARGET (2017)
Epiregulin Promotes Lung Metastasis of Salivary Adenoid Cystic Carcinoma
Wen-Wen Yang et al.
THERANOSTICS (2017)
Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
Chen Rachman-Tzemah et al.
CELL REPORTS (2017)
Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature
Tomoko Yamazaki et al.
CELL REPORTS (2017)
Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors
Maithili P. Dalvi et al.
CELL REPORTS (2017)
Fibronectin: How Its Aberrant Expression in Tumors May Improve Therapeutic Targeting
Jennifer Peyling Wang et al.
JOURNAL OF CANCER (2017)
Engineering the pre-metastatic niche
Brian A. Aguado et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy
Hanqiu Zheng et al.
CANCER CELL (2017)
MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases
Silvia Lemma et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
Alejandro Jimenez-Sanchez et al.
CELL (2017)
Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure
Gulfem Dilek Guler et al.
CANCER CELL (2017)
Pericytes are heterogeneous in their origin within the same tissue
Pedro Henrique Dias Moura Prazeres et al.
DEVELOPMENTAL BIOLOGY (2017)
Pre-metastatic niches: organ-specific homes for metastases
Hector Peinado et al.
NATURE REVIEWS CANCER (2017)
MAOA-Dependent Activation of Shh-IL6-RANKL Signaling Network Promotes Prostate Cancer Metastasis by Engaging Tumor-Stromal Cell Interactions
Jason Boyang Wu et al.
CANCER CELL (2017)
Endothelial Notch1 Activity Facilitates Metastasis
Elfriede Wieland et al.
CANCER CELL (2017)
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo
Nuno Guimaraes-Camboa et al.
CELL STEM CELL (2017)
Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
Brian B. Liau et al.
CELL STEM CELL (2017)
Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche
Diego Correa et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Eritoran inhibits S100A8-mediated TLR4/MD-2 activation and tumor growth by changing the immune microenvironment
A. Deguchi et al.
ONCOGENE (2016)
Structural ECM components in the premetastatic and metastatic niche
Anette M. Hoye et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)
Characteristics and Significance of the Pre-metastatic Niche
Yang Liu et al.
CANCER CELL (2016)
Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients
Niels Halama et al.
CANCER CELL (2016)
Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils
Yanfang Liu et al.
CANCER CELL (2016)
CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma
Colin W. Steele et al.
CANCER CELL (2016)
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche
David Clever et al.
CELL (2016)
Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver
Barbara Gruenwald et al.
GASTROENTEROLOGY (2016)
Distinctive properties of metastasis-initiating cells
Toni Celia-Terrassa et al.
GENES & DEVELOPMENT (2016)
Periostin promotes immunosuppressive premetastatic niche formation to facilitate breast tumour metastasis
Zhe Wang et al.
JOURNAL OF PATHOLOGY (2016)
Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis
M. Katie Conley-LaComb et al.
MOLECULAR CANCER (2016)
Visualization of immediate immune responses to pioneer metastatic cells in the lung
Mark B. Headley et al.
NATURE (2016)
Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer
Qing Chen et al.
NATURE (2016)
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
Sebastian R. Nielsen et al.
NATURE CELL BIOLOGY (2016)
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
Maia Vinogradova et al.
NATURE CHEMICAL BIOLOGY (2016)
The bone marrow pericyte: an orchestrator of vascular niche
Giuseppe Mangialardi et al.
REGENERATIVE MEDICINE (2016)
Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone
Trevor T. Price et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps
Juwon Park et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer
Maria Nilsson et al.
SCIENTIFIC REPORTS (2016)
The Osteogenic Niche Promotes Early-Stage Bone Colonization of Disseminated Breast Cancer Cells
Hai Wang et al.
CANCER CELL (2015)
Extracellular Metabolic Energetics Can Promote Cancer Progression
Jia Min Loo et al.
CELL (2015)
PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
Fanny Dupuy et al.
CELL METABOLISM (2015)
TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+Tumor-Initiating Cells
ZhengMing Wu et al.
CELL STEM CELL (2015)
The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?
Vicki Plaks et al.
CELL STEM CELL (2015)
The lack of type I interferon induces neutrophil-mediated pre-metastatic niche formation in the mouse lung
Ching-Fang Wu et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis
Marko Roblek et al.
JOURNAL OF CONTROLLED RELEASE (2015)
FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis
Bin-Zhi Qian et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Pulmonary Alveolar Macrophages Contribute to the Premetastatic Niche by Suppressing Antitumor T Cell Responses in the Lungs
Sharad K. Sharma et al.
JOURNAL OF IMMUNOLOGY (2015)
Bone metastasis and the metastatic niche
Guangwen Ren et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2015)
M-Trap: Exosome-Based Capture of Tumor Cells as a New Technology in Peritoneal Metastasis
Alexandre de la Fuente et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Blocking the Adhesion Cascade at the Premetastatic Niche for Prevention of Breast Cancer Metastasis
Shin-Ae Kang et al.
MOLECULAR THERAPY (2015)
Tumour exosome integrins determine organotropic metastasis
Ayuko Hoshino et al.
NATURE (2015)
Neutrophils support lung colonization of metastasis-initiating breast cancer cells
Stefanie K. Wculek et al.
NATURE (2015)
The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
Thomas R. Cox et al.
NATURE (2015)
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
Lin Zhang et al.
NATURE (2015)
IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
Seth B. Coffelt et al.
NATURE (2015)
Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
Miranda Y. Fong et al.
NATURE CELL BIOLOGY (2015)
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
Bruno Costa-Silva et al.
NATURE CELL BIOLOGY (2015)
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier
Naoomi Tominaga et al.
NATURE COMMUNICATIONS (2015)
NR2F1 controls tumour cell dormancy via SOX9-and RAR beta-driven quiescence programmes
Maria Soledad Sosa et al.
NATURE COMMUNICATIONS (2015)
CD44 increases the efficiency of distant metastasis of breast cancer
Suzanne McFarlane et al.
ONCOTARGET (2015)
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization
Yaiza del Pozo Martin et al.
CELL REPORTS (2015)
Concise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic Target
Yongmin Yan et al.
STEM CELLS TRANSLATIONAL MEDICINE (2015)
M-Trap: Exosome-Based Capture of Tumor Cells as a New Technology in Peritoneal Metastasis
Alexandre de la Fuente et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Combined Effects of Pericytes in the Tumor Microenvironment
Aline Lopes Ribeiro et al.
STEM CELLS INTERNATIONAL (2015)
CD44, hyaluronan, the hematopoietic stem cell, and leukemia-initiating cells
Margot Zoeller
FRONTIERS IN IMMUNOLOGY (2015)
Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
Kazuyoshi Shiga et al.
CANCERS (2015)
CD8+ T-cell immunosurveillance constrains lymphoid premetastatic myeloid cell accumulation
Wang Zhang et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Tissue Inhibitor of Metalloproteinases (TIMP)-1 Creates a Premetastatic Niche in the Liver Through SDF-1/CXCR4-Dependent Neutrophil Recruitment in Mice
Bastian Seubert et al.
HEPATOLOGY (2015)
A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4
M. T. Hansen et al.
ONCOGENE (2015)
Surviving at a Distance: Organ-Specific Metastasis
Anna C. Obenauf et al.
TRENDS IN CANCER (2015)
Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases
Sebastien Tabaries et al.
BREAST CANCER RESEARCH (2015)
Immune cell promotion of metastasis
Takanori Kitamura et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Extracellular matrix: A dynamic microenvironment for stem cell niche
Francesca Gattazzo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis
Weiying Zhou et al.
CANCER CELL (2014)
Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth
Kshitij Srivastava et al.
CANCER CELL (2014)
Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis
Manuel Valiente et al.
CELL (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Metastatic Stem Cells: Sources, Niches, and Vital Pathways
Thordur Oskarsson et al.
CELL STEM CELL (2014)
Lysyl Oxidase-Like 2 Is Critical to Tumor Microenvironment and Metastatic Niche Formation in Hepatocellular Carcinoma
Carmen Chak-Lui Wong et al.
HEPATOLOGY (2014)
Inhibition of demethylases by GSK-J1/J4
Bo Heinemann et al.
NATURE (2014)
Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
Laura Bonapace et al.
NATURE (2014)
Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
Lisa Sevenich et al.
NATURE CELL BIOLOGY (2014)
Remodelling the extracellular matrix in development and disease
Caroline Bonnans et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
Ting Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Human breast cancer metastases to the brain display GABAergic properties in the neural niche
Josh Neman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells
Makiko Ono et al.
SCIENCE SIGNALING (2014)
Extracellular RNA mediates and marks cancer progression
Jasmina S. Redzic et al.
SEMINARS IN CANCER BIOLOGY (2014)
Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis
Esak Lee et al.
NATURE COMMUNICATIONS (2014)
Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB
Amy Chow et al.
SCIENTIFIC REPORTS (2014)
Mechanisms of disseminated cancer cell dormancy: an awakening field
Maria Soledad Sosa et al.
NATURE REVIEWS CANCER (2014)
The pre-metastatic niche: finding common ground
Jaclyn Sceneay et al.
CANCER AND METASTASIS REVIEWS (2013)
Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells
Alexander Roesch et al.
CANCER CELL (2013)
Mesenchymal stem cell signaling in cancer progression
Anja Torsvik et al.
CANCER TREATMENT REVIEWS (2013)
CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches
Karin Williams et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2013)
Isolation and Phenotypic Characterization of Colorectal Cancer Stem Cells With Organ-Specific Metastatic Potential
Wenchao Gao et al.
GASTROENTEROLOGY (2013)
Inhibition of Breast Cancer Metastasis by Resveratrol-Mediated Inactivation of Tumor-Evoked Regulatory B Cells
Catalina Lee-Chang et al.
JOURNAL OF IMMUNOLOGY (2013)
Circulating Fibrocytes Prepare the Lung for Cancer Metastasis by Recruiting Ly-6C+ Monocytes Via CCL2
Hendrik W. van Deventer et al.
JOURNAL OF IMMUNOLOGY (2013)
Radiation-Induced Equilibrium Is a Balance between Tumor Cell Proliferation and T Cell-Mediated Killing
Hua Liang et al.
JOURNAL OF IMMUNOLOGY (2013)
TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling
Paloma Bragado et al.
NATURE CELL BIOLOGY (2013)
Premetastatic soil and prevention of breast cancer brain metastasis
Yan Liu et al.
NEURO-ONCOLOGY (2013)
Neutrophil chemokines secreted by tumor cells mount a lung antimetastatic response during renal cell carcinoma progression
M. A. Lopez-Lago et al.
ONCOGENE (2013)
GAS6 Receptor Status Is Associated with Dormancy and Bone Metastatic Tumor Formation
Russell S. Taichman et al.
PLOS ONE (2013)
Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci
Sachie Hiratsuka et al.
NATURE COMMUNICATIONS (2013)
The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium Is Critical for the Establishment of Lung Metastases
Takashi Minami et al.
CELL REPORTS (2013)
Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway
Monika Julia Wolf et al.
CANCER CELL (2012)
S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites
Jiehui Deng et al.
CANCER CELL (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
The evolving concept of cancer and metastasis stem cells
Irene Baccelli et al.
JOURNAL OF CELL BIOLOGY (2012)
The extracellular matrix: A dynamic niche in cancer progression
Pengfei Lu et al.
JOURNAL OF CELL BIOLOGY (2012)
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
Carmen Chak-Lui Wong et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Hector Peinado et al.
NATURE MEDICINE (2012)
Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance
Ingrid G. Winkler et al.
NATURE MEDICINE (2012)
Bench to bedside: elucidation of the OPG-RANK-RANKL pathway and the development of denosumab
David L. Lacey et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Building the niche: The role of the S100 proteins in metastatic growth
Eugene Lukanidin et al.
SEMINARS IN CANCER BIOLOGY (2012)
Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer
Ende Zhao et al.
ONCOIMMUNOLOGY (2012)
Integrins and bone metastasis: Integrating tumor cell and stromal cell interactions
Jochen G. Schneider et al.
BONE (2011)
VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors
Xin Lu et al.
CANCER CELL (2011)
Macrophage Binding to Receptor VCAM-1 Transmits Survival Signals in Breast Cancer Cells that Invade the Lungs
Qing Chen et al.
CANCER CELL (2011)
Tumor-Derived Jagged1 Promotes Osteolytic Bone Metastasis of Breast Cancer by Engaging Notch Signaling in Bone Cells
Nilay Sethi et al.
CANCER CELL (2011)
Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung
Zvi Granot et al.
CANCER CELL (2011)
Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis
Zhiyong Mi et al.
CARCINOGENESIS (2011)
Hyaluronan and mesenchymal stem cells: from germ layer to cartilage and bone
Liliana Astachov et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2011)
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
Bin-Zhi Qian et al.
NATURE (2011)
Bone metastasis: mechanisms and therapeutic opportunities
Larry J. Suva et al.
NATURE REVIEWS ENDOCRINOLOGY (2011)
Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis
T. Tomita et al.
ONCOGENE (2011)
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
Carmen Chak-Lui Wong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Dynamic interplay between the collagen scaffold and tumor evolution
Mikala Egeblad et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
The extracellular matrix at a glance
Christian Frantz et al.
JOURNAL OF CELL SCIENCE (2010)
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
Janine T. Erler et al.
CANCER CELL (2009)
The Extracellular Matrix: Not Just Pretty Fibrils
Richard O. Hynes
SCIENCE (2009)
All MSCs are pericytes?
Arnold I. Caplan
CELL STEM CELL (2008)
The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase
Sachie Hiratsuka et al.
NATURE CELL BIOLOGY (2008)
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
Johan Skog et al.
NATURE CELL BIOLOGY (2008)
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
Antoine E. Karnoub et al.
NATURE (2007)
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Hadi Valadi et al.
NATURE CELL BIOLOGY (2007)
Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
Sachie Hiratsuka et al.
NATURE CELL BIOLOGY (2006)
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
RN Kaplan et al.
NATURE (2005)
Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation
B Fogelgren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow
A Avigdor et al.
BLOOD (2004)
Exosomes:: Composition, biogenesis and function
C Théry et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Urokinase receptor and fibronectin regulate the ERKMAPK to p38MAPK activity ratios that determine carcinoma cell proliferation or dormancy in vivo
JA Aguirre-Ghiso et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Share Paper
